Cystatin C and uncontrolled hypertension
| dc.authorid | 0000-0003-2995-8792 | |
| dc.authorid | 0000-0003-1516-1811 | |
| dc.authorid | 0000-0003-0230-6575 | |
| dc.authorid | 0000-0002-4281-0867 | |
| dc.contributor.author | Omaygenç, Mehmet Onur | |
| dc.contributor.author | Özcan, Özgür Ulaş | |
| dc.contributor.author | Çakal, Beytullah | |
| dc.contributor.author | Karaca, Oğuz | |
| dc.date.accessioned | 2020-11-20T05:31:37Z | |
| dc.date.available | 2020-11-20T05:31:37Z | |
| dc.date.issued | 2020 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | |
| dc.description.abstract | Objective: Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study.Methods: We screened 1037 adults residing in both rural and urban communities. They were grouped based on their diagnosis and control of hypertension.Results: Serum cystatin C levels in patients with uncontrolled hypertension were higher than those in patients with controlled hypertension (0.98 +/- 0.23 mg/L vs. 0.89 +/- 0.19 mg/L, p=0.001). However, serum creatinine levels were similar between these groups (0.72 +/- 0.20 mg/dL vs. 0.70 +/- 0.18 mg/dL, p=0.89). Serum cystatin C levels increased the probability of uncontrolled hypertension independent from confounding factors (odds ratio, 1.48; 95% confidence interval, 1.09-5.64; p=0.03).Conclusion: Subtle kidney dysfunction may be detected using serum cystatin C concentrations among patients with poor blood pressure control and normal serum creatinine levels. | |
| dc.identifier.citation | Omaygenç, M. O., Özcan, Ö. U., Çakal, B. ve Karaca, O. (2020). Cystatin C and uncontrolled hypertension. Anatolian Journal of Cardiology, 24(5), 309-315. https://dx.doi.org/10.14744/AnatolJCardiol.2020.78974 | |
| dc.identifier.doi | 10.14744/AnatolJCardiol.2020.78974 | |
| dc.identifier.endpage | 315 | |
| dc.identifier.issn | 2149-2263 | |
| dc.identifier.issn | 2149-2271 | |
| dc.identifier.issue | 5 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 309 | |
| dc.identifier.uri | https://dx.doi.org/10.14744/AnatolJCardiol.2020.78974 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/6033 | |
| dc.identifier.volume | 24 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Turkish Society of Cardiology | |
| dc.relation.ispartof | Anatolian Journal of Cardiology | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Chronic Kidney Disease | |
| dc.subject | Creatinine | |
| dc.subject | Cystatin C | |
| dc.subject | Hypertension | |
| dc.title | Cystatin C and uncontrolled hypertension | |
| dc.type | Article |
