Histopathological investigation of onychomycosis frequency in psoriatic nails using periodic acid-schiff staining

dc.authorid0000-0002-0011-7570
dc.authorid0000-0001-5057-0405
dc.authorid0000-0002-7022-913X
dc.authorid0000-0002-4119-9939
dc.authorid0000-0002-9870-9733
dc.authorid0000-0002-0600-5801
dc.contributor.authorYüksel, Mavişe
dc.contributor.authorBalevi, Ali
dc.contributor.authorÖzdemir, Mustafa
dc.contributor.authorTürkmen, İlknur
dc.contributor.authorÇakıter, Alkım Ünal
dc.contributor.authorSaraç, Esra
dc.contributor.authorÜnal, Mehmet
dc.contributor.authorÇalış, Elif
dc.date.accessioned2020-11-05T07:07:04Z
dc.date.available2020-11-05T07:07:04Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.description.abstractBackground and Design: Psoriasis nail involvement is clinically similar to onychomycosis. Especially subungual hyperkeratosis and onycholysis are also common in both nail diseases. These two diseases may be seen separetely or together. The aim of this study was to compare the frequency of onychomycosis with control group in patients with psoriasis and to determine the factors predisposing to onychomycosis in patients with psoriasis.Materials and Methods: The study included 43 patients with psoriasis who were admitted to Istanbul Medipol Mega University, Clinic of Dermatology between 2017 and 2018 and 43 control patients who did not have psoriasis and had nail dystrophy. Participants who received systemic corticosteroid, methotrexate, cyclosporine, and systemic antifungal treatment 4 months ago and who received topical antifungal treatment 4 weeks ago were excluded from the study. The nail samples were examined histochemically with periodic acid-Schiff (PAS) stain.Results: Onychomycosis was detected in 11 patients with psoriasis (25.6%) (hand and/or foot), while in 17 patients (39.5%) in control group. There was no statistically significant difference between two groups (p=0.170). In control group, toe nail onychomycosis was significantly higher than in the psoriatic group (p=0.024). It was noteworthy that onychomycosis was statistically significant in the group with high educational level and low Psoriasis Area Severity Index (p<0.05 and p=0.021, respectively).Conclusion: In this study, we determined that nail psoriasis is not a risk factor for onychomycosis by histopathological examination of fungal samples with PAS staining.
dc.identifier.citationYüksel, M., Balevi, A., Özdemir, M., Türkmen, İ., Çakıter, A. Ü., Saraç, E. ... Çalış, E. (2020). Histopathological investigation of onychomycosis frequency in psoriatic nails using periodic acid-schiff staining. Turkderm-Turkish Archives of Dermatology and Venereology, 54(3), 103-107. https://dx.doi.org/10.4274/turkderm.galenos.2020.23090
dc.identifier.doi10.4274/turkderm.galenos.2020.23090
dc.identifier.endpage107
dc.identifier.issn2717-6398
dc.identifier.issn2651-5164
dc.identifier.issue3
dc.identifier.scopusqualityQ4
dc.identifier.startpage103
dc.identifier.urihttps://dx.doi.org/10.4274/turkderm.galenos.2020.23090
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5998
dc.identifier.volume54
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherDeri ve Zührevi Hastalıklar Derneği
dc.relation.ispartofTurkderm-Turkish Archives of Dermatology and Venereologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectOnychomycosis
dc.subjectPsoriasis
dc.subjectPeriodic Acid-Schiff
dc.titleHistopathological investigation of onychomycosis frequency in psoriatic nails using periodic acid-schiff staining
dc.typeArticle

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