Bioactive peptides: An alternative therapeutic approach for cancer management

dc.contributor.authorGhadiri, Nooshin
dc.contributor.authorJavidan, Moslem
dc.contributor.authorSheikhi, Shima
dc.contributor.authorTaştan, Özge
dc.contributor.authorParodi, Alessandro
dc.contributor.authorLiao, Ziwei
dc.contributor.authorTayybi Azar, Mehdi
dc.contributor.authorGanjalıkhani-Hakemi, Mazdak
dc.date.accessioned2024-02-20T12:49:03Z
dc.date.available2024-02-20T12:49:03Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.description.abstractCancer is still considered a lethal disease worldwide and the patients’ quality of life is affected by major side effects of the treatments including post-surgery complications, chemo-, and radiation therapy. Recently, new therapeutic approaches were considered globally for increasing conventional cancer therapy efficacy and decreasing the adverse effects. Bioactive peptides obtained from plant and animal sources have drawn increased attention because of their potential as complementary therapy. This review presents a contemporary examination of bioactive peptides derived from natural origins with demonstrated anticancer, ant invasion, and immunomodulation properties. For example, peptides derived from common beans, chickpeas, wheat germ, and mung beans exhibited antiproliferative and toxic effects on cancer cells, favoring cell cycle arrest and apoptosis. On the other hand, peptides from marine sources showed the potential for inhibiting tumor growth and metastasis. In this review we will discuss these data highlighting the potential befits of these approaches and the need of further investigations to fully characterize their potential in clinics.
dc.description.sponsorship32000802 ; 202102020181 ; ZSYXM202203 ; 21-75-30020en_US
dc.identifier.citationGhadiri, N., Javidan, M., Sheikhi, S., Taştan, Ö., Parodi, A., Liao, Z. ... Ganjalıkhani-Hakemi, M. (2024). Bioactive peptides: An alternative therapeutic approach for cancer management. Frontiers in Immunology, 15. https://dx.doi.org/10.3389/fimmu.2024.1310443
dc.identifier.doi10.3389/fimmu.2024.1310443
dc.identifier.issn1664-3224
dc.identifier.pmid38327525
dc.identifier.scopus2-s2.0-85184230166
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://dx.doi.org/10.3389/fimmu.2024.1310443
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12292
dc.identifier.volume15
dc.identifier.wos001156577200001en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGanjalıkhani-Hakemi, Mazdak
dc.language.isoen
dc.publisherFrontiers Media SA
dc.relation.ispartofFrontiers in Immunologyen_US
dc.relation.publicationcategoryDiğer
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAnticancer
dc.subjectBioactive Peptide
dc.subjectCancer Therapy
dc.subjectImmunomodulation
dc.subjectCancer Immunotherapy
dc.titleBioactive peptides: An alternative therapeutic approach for cancer management
dc.typeReview Article

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