Pharmaceutical applications of a nanospectroscopic technique: Surface-enhanced Raman spectroscopy

Basit Öğe Kaydı
dc.contributor.authorYılmaz, Hülya
dc.contributor.authorYılmaz, Deniz
dc.contributor.authorÇulha Taşkın, İrem
dc.contributor.authorÇulha, Mustafa
dc.date.accessioned2022-04-01T06:04:05Z
dc.date.available2022-04-01T06:04:05Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractSurface-enhanced Raman spectroscopy (SERS) is a very sensitive technique offering unique opportunities for detection and identification of molecules and molecular structures at extremely low concentrations even in complex sample matrixes. Since a nanostructured noble metal surface is required for the enhancement of Raman scattering, the acquired spectral information naturally originates from nanometer size domains making it a nanospectroscopic technique by breaking the diffraction limit of light. In this review, first Raman spectroscopy, its comparison to other related techniques, its modes and instrumentation are briefly introduced. Then, the SERS mechanism, substrates and the parameters influencing a SERS experiment are discussed. Finally, its applications in pharmaceuticals including drug discovery, drug metabolism, multifunctional chemo-photothermal-therapy-delivery-release-imaging, drug stability and drug/metabolite detection in complex biological samples are summarized and elaborated.
dc.identifier.citationYılmaz, H., Yılmaz, D., Çulha Taşkın, İ. ve Çulha, M. (2022). Pharmaceutical applications of a nanospectroscopic technique: Surface-enhanced Raman spectroscopy. Advanced Drug Delivery Reviews, 184. https://doi.org/10.1016/j.addr.2022.114184
dc.identifier.doi10.1016/j.addr.2022.114184
dc.identifier.issn0169-409X
dc.identifier.pmid35306126
dc.identifier.scopus2-s2.0-85126579245
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.addr.2022.114184
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9190
dc.identifier.volume184
dc.identifier.wos000793595700007en_US
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇulha Taşkın, İrem
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofAdvanced Drug Delivery Reviewsen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectBiomedical Imaging
dc.subjectDetection
dc.subjectDrug Delivery
dc.subjectDrug Discover
dc.subjectDrug Stability
dc.subjectNanospectroscopy
dc.subjectPharmaceuticals
dc.subjectSurface-Enhanced Raman Spectroscopy (SERS)
dc.titlePharmaceutical applications of a nanospectroscopic technique: Surface-enhanced Raman spectroscopy
dc.typeReview Article

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
Taskin-Irem-2022.pdf
Boyut:
4.3 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Diğer Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu