Nadir görülen bir gestasyonel trofoblastik neoplazi formu; plasental site trofoblastik tümör ve literatürün gözden geçirilmesi

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dc.authorid0000-0003-0640-4420
dc.contributor.authorAktün, Lebriz Hale
dc.contributor.authorYorgunlar, Betül
dc.contributor.authorNaki, Murat Mehmet
dc.contributor.authorÖzdemir, Suna
dc.contributor.authorKöse, Faruk Mehmet
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:36:02Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:36:02Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractPlacental site trophoblastic tumor (PSTT) is one of the gestational trophoblastic neoplasias (GTN) arising from intermediate gestational trophoblasts. It is a rarely seen type of GTN’s, and 300 cases have been reported in the literature so far (1). Is also covers 1-2%of trophoblastic tumors (2). Having a low incidence limits the understanding of its etiology and clinical pathology. Typically seen in women of reproductive age and term pregnancy may occur months or years later. It may occur after any pregnancy as well. PTTY is not easy to diagnose in the early stages because patients often present with irregular vaginal bleeding or amenorrhea. ß-HCG levels are generally lower than those patients moderately high and choriocarcinoma (3). Infiltration of the proliferative growth myometrial muscle in the intermediate trophoblast is required for diagnosis. İntrauterine aspiration is inadequate and uterine curettage is required for diagnosis. While GTNs are responsive to chemotherapy, PSTTs are relatively chemoresistance due to the weak biological behavior (3). PSTT grows slowly, spreads into the uterus, and makes metastatis passing to lymph nodes. Hysterectomy is the most effective treatment to the non-metastatic disease (3). For metastatic patients and with high mitotic indexed large tumor adjuvant chemotherapy is recommended. We aim to provide a PSTT which is a rare form of GTNs’case accompanying the literature in the case report.
dc.identifier.citationAktün, L. H., Yorgunlar, B., Naki, M. M., Özdemir, S. ve Köse, F. M. (2015). Nadir görülen bir gestasyonel trofoblastik neoplazi formu; plasental site trofoblastik tümör ve literatürün gözden geçirilmesi. Türk Jinekolojik Onkoloji Dergisi, 18(3), 104-107.
dc.identifier.endpage107
dc.identifier.issn1301-8841
dc.identifier.issue3
dc.identifier.scopusqualityQ4
dc.identifier.startpage104
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1039
dc.identifier.volume18
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherGüneş Kitap Kirtasiye
dc.relation.ispartofTürk Jinekolojik Onkoloji Dergisien_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGestational Trophoblastic Neoplasia
dc.subjectTrophoblastic Tumor
dc.titleNadir görülen bir gestasyonel trofoblastik neoplazi formu; plasental site trofoblastik tümör ve literatürün gözden geçirilmesi
dc.title.alternativeA rare gestational trophoblastic neoplasia form; placental site trophoblastic Tumor and literature review
dc.typeReview Article

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