Synthesis and antifungal activity evaluation of New 1,2,4-triazole derivatives bearing salicylidene hydrazide moiety

Basit Öğe Kaydı
dc.contributor.authorDemirayak, Şeref
dc.contributor.authorKayagil, İsmail
dc.contributor.authorYurttaş, Leyla
dc.contributor.authorEr, Sevda
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:38Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:38Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000364521600009
dc.description.abstractA series of new N'-(arylidene)-2-[(1-(4-nitrophenyl)-1H-1,2,4-triazol-3-yl)oxy]acetohydrazide derivatives (116) were prepared and tested for theira ntifungal activity against six plant pathogens, three human pathogens and two non-pathogen microorganisms. The target compounds were obtained with a multi-step reaction starting from 4-substitutedarylhydrazine derivatives and the structures of final compounds have been elucidated with IR, NMR, Mass spectroscopy data and elemental analysis results. The antifungal activity of the compounds was determined against eleven different Fusarium, Trichoderma, Aspergillus and Penicilliumspeciesby using microdilution method. Most of the target compounds showed excellent antifungal activity against a variety of fungal pathogens.
dc.identifier.citationDemirayak, Ş., Kayagil, İ., Yurttaş, L. ve Er, S. (2016). Synthesis and antifungal activity evaluation of New 1,2,4-triazole derivatives bearing salicylidene hydrazide moiety. Letters In Drug Design & Discovery, 13(2), 178-184. https://dx.doi.org/10.2174/1570180812666150723001545
dc.identifier.doi10.2174/1570180812666150723001545
dc.identifier.endpage184
dc.identifier.issn1570-1808
dc.identifier.issn1875-628X
dc.identifier.issue2
dc.identifier.scopusqualityQ2
dc.identifier.startpage178
dc.identifier.urihttps://dx.doi.org/10.2174/1570180812666150723001545
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3381
dc.identifier.volume13
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBentham Science Publ Ltd
dc.relation.ispartofLetters In Drug Design & Discoveryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSalicylidene Hydrazide
dc.subject1,2,4-Triazole
dc.subjectAntifungal Activity
dc.titleSynthesis and antifungal activity evaluation of New 1,2,4-triazole derivatives bearing salicylidene hydrazide moiety
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Eczacılık Fakültesi Makale Koleksiyonu
Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu