Empiric treatment of children with gastroesophageal reflux- like symptoms: Effect of proton pump inhibitors

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dc.authorid0000-0003-4479-3404
dc.authorid0000-0001-5658-1295
dc.contributor.authorGündüz, Mehmet
dc.contributor.authorYamaç, Pınar
dc.contributor.authorBaysoy, Gökhan
dc.date.accessioned08.07.201910:49:13
dc.date.accessioned2019-07-08T20:18:49Z
dc.date.available08.07.201910:49:13
dc.date.available2019-07-08T20:18:49Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractGastroesophageal reflux disease is an important cause of morbidity in childhood. Although various diagnostic methods are available, short course of empiric treatment with a proton pump inhibitor is widely used in adults as a diagnostic test. Data about empiric treatment is scarce in children. The aim of this study is to evaluate the effectiveness of empiric treatment of reflux-like symptoms in children.Pediatric gastroenterology outpatient files were searched and patients with a diagnosis of gastroesophageal reflux were found. Patient complaints, history and the treatments provided were recorded. Treatment naive patients older than 2 years of age with symptoms suggestive of gastroesophageal reflux were selected and included if they were given empiric treatment with a proton pump inhibitor. Empiric treatment was found to be effective in 78% of patients. Treatment response tended to be better in children older than 5 years of age. Of the 22 non-responders 9 underwent endoscopy and pathological findings were discovered in 7 of them. Treatment of children with gastroesophageal reflux symptoms with a proton pump inhibitor might significantly decrease the need for extensive evaluations. However it is important to investigate non-responders to empiric therapy, as it seems there might be high probability of pathological findings.
dc.identifier.citationGündüz, M., Yamaç, P. ve Baysoy, G. (2015). Empiric treatment of children with gastroesophageal reflux-like symptoms: Effect of proton pump inhibitors. Turkish Journal of Pediatrics, 57(5), 482-486.
dc.identifier.endpage486
dc.identifier.issn0041-4301
dc.identifier.issue5
dc.identifier.scopusqualityQ3
dc.identifier.startpage482
dc.identifier.urihttps://hdl.handle.net/20.500.12511/497
dc.identifier.volume57
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish National Pediatric Society
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChildren
dc.subjectEmpiric Treatment
dc.subjectGastroesophageal Reflux
dc.subjectProton Pump Inhibitor
dc.titleEmpiric treatment of children with gastroesophageal reflux- like symptoms: Effect of proton pump inhibitors
dc.typeArticle

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