Surgery for intractable temporal lobe epilepsy: experience of a single institution

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dc.authorid0000-0002-0106-9363
dc.contributor.authorKurt, Gökhan
dc.contributor.authorTönge, Mehmet
dc.contributor.authorÇeltikçi, Emrah
dc.contributor.authorÇapraz, İrem
dc.contributor.authorSerdaroğlu, Ayşe
dc.contributor.authorBilir, Erhan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:03:53Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:03:53Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.descriptionWOS: 000343068800025
dc.descriptionPubMed ID: 25539559
dc.description.abstractBackground/aim: In the treatment of epilepsy, encouraging results have been achieved with surgical treatment, especially for temporal lobe epilepsy (TLE). Drug resistance must be diagnosed as early as possible, because the ensuing seizures can be eliminated surgically via temporal lobe surgery in a high percentage (70%-90%) of patients. In this study we share our experience, in a single institution, of surgical treatment of intractable TLE. Materials and methods: Between March 2006 and November 2010 we performed 127 corticoamygdalohippocampectomy (CAH) procedures. All CAN surgical procedures were done as described by Niemeyer's technique. Resection lengths were 4-4.5 cm from the temporal pole. Results: At the end of 24 months, 79.7% (n = 94) patients were still on antiepileptic medications, with 55 of them on a decreased number or dose of drugs, and 20.3 (n = 24) patients were antiepileptic drug-free. Postoperative Engel's classes were 1, 2, and 3 in 87.2%, 5.08%, and 7.6%, respectively. There was no mortality in follow-up, and dysphasia in 1 patient (0.84%) was the only morbidity. Conclusion: In our series we found that the outcome of surgery is associated with careful patient selection, which requires a detailed investigation of the patients. Our final conclusion is that outcome scores are independent of age, pathology, or sex but are dependent on correct patient selection.
dc.identifier.citationKurt, G., Tönge, M., Çeltikçi, E., Çapraz, İ., Serdaroğlu, A. ve Bilir, E. (2014). Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turkish Journal of Medical Sciences, 44(5), 866-870. https://dx.doi.org/10.3906/sag-1307-30
dc.identifier.doi10.3906/sag-1307-30
dc.identifier.endpage870
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5
dc.identifier.scopusqualityQ3
dc.identifier.startpage866
dc.identifier.urihttps://dx.doi.org/10.3906/sag-1307-30
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3960
dc.identifier.volume44
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherThe Scientific and Technological Research Council of Turkey
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCorticoamygdalohippocampectomy
dc.subjectEpilepsy Surgery
dc.subjectHippocampal Sclerosis
dc.subjectMesial Temporal Lobe
dc.subjectOutcome
dc.subjectTemporal Lobectomy
dc.titleSurgery for intractable temporal lobe epilepsy: experience of a single institution
dc.typeArticle

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