Instant and early efficacy of gamma knife treatment on trigeminal neuralgia

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dc.authorid0000-0002-0399-7569
dc.authorid0000-0002-1847-2562
dc.authorid0000-0002-9221-975X
dc.contributor.authorAltınok, Ayşe
dc.contributor.authorKarancı, Türker
dc.contributor.authorÖzbek, Arif
dc.contributor.authorAlbayrak, Serdar Baki
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:03:36Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:03:36Z
dc.date.issued2018
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyasyon Onkolojisi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.descriptionWOS: 000457150800005
dc.description.abstractOBJECTIVE Trigeminal neuralgia (TN) is a common craniofacial pain syndrome manifested by the episodes of severe lancinating pain along the sensory region of the trigeminal nerve. Vascular compression theory has been postulated as the main cause of TN in the root entry zone of the trigeminal nerve. Microvascular decompression surgery is the most effective surgical option for the treatment of TN. Gamma knife surgery (GKS) is a minimally invasive treatment for drug-resistant trigeminal neuralgia (TN). We aimed to investigate the instant and early pain relief in 12 consecutive patients. METHODS This clinical study was conducted at the Department of Radiation Oncology, Medipol University, Turkey. The patient population consisted of 12 consecutive patients having medically refractory TN, with a median age of 60.5 (ranging from 50 to 77 years). Patients underwent GKS between March and January 2016, using the Gamma Knife Perfexion Model. A single 4 mm isocenter was positioned in the cisternal portion of the trigeminal nerve, and the mean maximum dose of 65 Gy (60-70 Gy) was delivered. RESULTS Satisfactory pain relief without any major complications was evident in all patients. The pain relief started after 1 hour to 3 days following the gamma knife procedure. CONCLUSION As a novel contribution to the relevant literature, instant and early pain relief was evident in all patients. In this context, a randomized prospective clinical trial with a larger patient population is necessary to optimize the instant and early efficacy of GKS in the treatment of TN.
dc.identifier.citationAltınok, A., Karancı, T., Özbek, A. ve Albayrak, S. B. (2018). Instant and early efficacy of gamma knife treatment on trigeminal neuralgia. Turkish Journal of Oncology, 33(4), 154-158. https://dx.doi.org/10.5505/tjo.2018.1770
dc.identifier.doi10.5505/tjo.2018.1770
dc.identifier.endpage158
dc.identifier.issn1300-7467
dc.identifier.issue4
dc.identifier.scopusqualityQ4
dc.identifier.startpage154
dc.identifier.urihttps://dx.doi.org/10.5505/tjo.2018.1770
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3907
dc.identifier.volume33
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKare Publishing
dc.relation.ispartofTurkish Journal of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGamma Knife
dc.subjectRadiosurgery
dc.subjectTrigeminal Neuralgia
dc.titleInstant and early efficacy of gamma knife treatment on trigeminal neuralgia
dc.typeArticle

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