The determine of possible drug interaction of clarithromycin

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dc.authorid0000-0002-6141-8676
dc.authorid0000-0001-6047-2796
dc.contributor.authorCeylan, Cengizhan
dc.contributor.authorKarataş Koçberber, Emine
dc.contributor.authorTaner, Neda
dc.contributor.authorBerk, Barkın
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:37Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:37Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Klinik Eczacılık Ana Bilim Dalı
dc.descriptionWOS: 000384561800054
dc.description.abstractPhenytoin is an antiepileptic drug which is eliminated by CYP2C9, CYP2C19 (less important: CYP2C18, CYP3A4) enzyme. Therapeutic concentration range is very important due to the narrow therapeutic drug levels. Targeted therapeutic concentration range is 10–20 mg/L (40–80 lmol/L) in blood serum for adults and children older than 3 months. Phenytoin has highly variable pharmacokinetics due to its complex of binding to Albumin (%90). It is dif?cult to determine the correct dosage of this drug because of signi?cant dose related toxicity. It is also important for inpatient in intensive care unit.
dc.identifier.citationCeylan, C., Koçberber, E., Taner, N. ve Berk, B. (2016). The determine of possible drug interaction of clarithromycin. International Journal of Clinical Pharmacy içinde (1341-1341. ss.).
dc.identifier.endpage1341
dc.identifier.issn2210-7703
dc.identifier.issn2210-7711
dc.identifier.issue5
dc.identifier.startpage1341
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2768
dc.identifier.volume38
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofInternational Journal of Clinical Pharmacyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPharmacology
dc.subjectPharmacy
dc.subjectClinical Pharmacy
dc.titleThe determine of possible drug interaction of clarithromycin
dc.typeConference Object

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