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Öğe Antimicrobial activity evaluation of three different medicinal plants against human pathogenic strains(Georg Thieme Verlag KG, 2023) Kahya, Sümeyye Elif; Karavuş, Şule Nur[Abstract Not Available]Öğe Mechanistic evaluation of the antiviral potential of two commercial herbal products(Georg Thieme Verlag KG, 2023) Karadağ, Ayşe Esra; Demirci, Fatih[Abstract Not Available]Öğe Comparison of In vitro Anti-inflammatory, COX-1/COX-2 and LOX inhibitory activities of Malva sylvestris L. leaves and flowers extract(Georg Thieme Verlag KG, 2023) Baydar, Rengin; Biltekin, Sevde Nur; Karadağ, Ayşe Esra[Abstract Not Available]Öğe Evaluation and prediction of depression and anxiety among patients with chronic disease conditions during the pandemic COVID-19 era(Springer, 2022) Al-Taie, Anmar Hasan Kashkool; Khalaf, D. A. Mohd; Victoria, A. O.; Köseoğlu, A.[Abstract Not Available]Öğe Patterns of knowledge and safety use of energy drinks use during COVID pandemic era among athletes and sport adolescents in Kyrenia-northern Cyprus(Springer, 2022) Al-Taie, Anmar Hasan Kashkool; Victoria, A. O.; Köseoğlu, A.[Abstract Not Available]Öğe Impact of clinical pharmacist intervention on taxane-related lymphedema among breast cancer patients(Springer, 2022) Köseoğlu, A.; Al-Taie, Anmar Hasan Kashkool[Abstract Not Available]Öğe Administration of Ad5/chitosan/PEG-aptamer vector delivering PDGF-D shRNA decreases tumor growth in rat breast cancer model(Mary Ann Liebert, 2021) Ekentok Atıcı, Ceyda; Akbuğa, Fatma Jülide[Abstract Not Available]Öğe The moleculer mechanism of squalen on cisplatin-induced nefrotoxicity(Wiley-Blackwell, 2016) Şakul Sayın, Ayşe Arzu; Ozansoy, Mehmet; Ayla, Şule; Günal, Mehmet Yalçın; Yozgat, Yasemin; Kazancıoğlu, Rumeysa; Şahin, Kazım; Kılıç, Ülkan[Abstract Not Available]Öğe Type 2 diabetes risk assessment program for children and adolescents at the community pharmacy setting(Springer, 2017) Apıkoğlu Rabuş, Şule; Karataş Koçberber, Emine; İzzettin, Fikret Vehbi[Abstract Not Available]Öğe Prognostic significance of tumour tissue NeuGcGM3 ganglioside expression and predictive value of circulating tumour cell count monitoring in patients receiving racotumomab immunotherapy(Oxford University Press, 2019) Üskent, Necdet; Ayla, Şule; Mandel, Nil Molinas; Özkan, Metin; Teomete, Mehmet; Baloğlu, Hüseyin; Aydinçer, Cenk; Yergök, H.; Doğan, Erkan; Berk, Barkın; Yazar, Aziz[Abstract Not Available]Öğe The new sources to improve the knowledge level of pharmacist(Springer, 2017) Karataş Koçberber, Emine; Koçberber, Yusuf Niyazi[Abstract Not Available]Öğe The effect of carnitine against acrylamide-induced toxicity in rat lung and liver tissues(Elsevier Ireland Ltd, 2016) Aydemir, Sezgin; Güçlü, Hande; Özkan, Nazlı Topfedaisi; Yüksel, Meral; Erdoğan, Nusret; Omurtag, Gülden ZehraAcrylamide (ACR) has the potential for cytotoxic and genotoxic effects by decreasing oxidative defense system and is known to be neurotoxic, hepatotoxic and carcinogenic to humans. Carnitine plays an important role in the transport of long-chain fatty acids through the mitochondrial membrane for their beta-oxidation and in ATP production in peripheral tissues. The purpose of the study is conducted for determine the effect of carnitine on acrylamide induced tissue injury in rats.Öğe Power of antimicrobial stewardship(Springer, 2018) Dinleyici, Rümeysa; Yılmaz, Mesut[Abstract Not Available]Öğe A pilot study on effects of combination usage of curcumin and melatonin on cisplatin treatment(Elsevier Ireland Ltd, 2016) Özdatlı, Şükran; Kaşıkçıoğlu, G.; Göçmen, Emrah; Rüzgar, Melih; Omurtag, Gülden ZehraCisplatin is an antitumor drug widely used in the treatmentof many malignant tumors. And also some studies show thatmelatonin and curcumin have antitumor activity via several mech-anisms including theirs in addition to theirs potent antioxidantactions. This study was performed to evaluate the effect of cur-cumin and melatonin on the cytotoxicity induced by cisplatin inthe human breast cancer cell line (MCF-7). The cells were treatedwith melatonin or cisplatin or curcumin for 24 and 48 h. Cellviability was quantified using the 3-(4,5-dimethyl-2-thiazolyl)-Öğe The determine of possible drug interaction of clarithromycin(Springer, 2016) Ceylan, Cengizhan; Karataş Koçberber, Emine; Taner, Neda; Berk, BarkınPhenytoin is an antiepileptic drug which is eliminated by CYP2C9, CYP2C19 (less important: CYP2C18, CYP3A4) enzyme. Therapeutic concentration range is very important due to the narrow therapeutic drug levels. Targeted therapeutic concentration range is 10–20 mg/L (40–80 lmol/L) in blood serum for adults and children older than 3 months. Phenytoin has highly variable pharmacokinetics due to its complex of binding to Albumin (%90). It is dif?cult to determine the correct dosage of this drug because of signi?cant dose related toxicity. It is also important for inpatient in intensive care unit.Öğe Prescribing pattern of PPI and clopidogrel in community pharmacies in Turkey(Springer, 2016) Karataş Koçberber, Emine; Abunahlah, Nibal; Berk, BarkınBackground & Objectives: Proton Pump Inhibitors (PPIs) are among the most prescribed medications in Turkey. The use of proton pump inhibitors is one of the risk factors associated with treatment failure or unresponsiveness for clopidogrel therapy. Our objective is to describe the prescribing patterns of proton pump inhibitors among the cardiovascular patient in Turkish population. Methodology & Setting: A retrospective study was conducted in 100 patients’ prescriptions that contain clopidogrel were collected in a period of 3 months from three community pharmacies. Demographic variables were collected from the pharmacy online system and indications for both proton pump inhibitor and clopidrogel were identified. Patterns of drug prescriptions were evaluated and the change in prescription with time was also taken into account. Main outcome measures: The use of PPI like lansoprazol, esomeprazol, pantoprazole, omeprazole, rabeprazole, and clopidogrel were evaluated by using pharmacy medication record system within 6 months period. Prescriptions that include PPI and clopidogrel simultaneously were highlighted. Drug-drug interaction was checked using Medscape drug interaction checker. Results: In the current study, findings showed that, 74% of patients receiving clopidogrel and PPI simultaneously where 26% of patients had received clopidogrel with PPI in the same prescription. The prescription patterns of PPI were found as 25%, 13%, 28%, and 8% for lansoprazole, esomeprazole, pantoprazole and rabeprazole, respectively. Significant drug-drug interaction between PPI and clopidogrel was detected in 38% of patients, 31.7% of these patients received both drugs at the same prescription. 22.9% of the patients had different PPI in the medication histories, 16% of these changes were incorrectly and 6.9% were correctly done. Conclusion: Although most of the prescriptions contain pantoprazole or rabeprazole, there are still some prescriptions that contain lansoprazole in combination with clopidogrel, may reduce the effectiveness of clopidogrel in preventing heart attack or stroke. Community pharmacist must be aware of these types of interaction and must play a role in preventing and monitoring them by calling the prescribers if possible. Increasing the community pharmacist’s knowledge towards these types of interactions will lead to decrease the negative economic and health impacts of drug interactions.Öğe Biological activities of the essential oil, fruit and root extracts of ferula drudeana korovin(Georg Thieme Verlag Kg, 2013) Miski, Mahmut; Kürkçüoğlu, Mine; İşcan, Gökalp; Göğer, Fatih; Tosun, Fatma[Abstract Not Available]Öğe A prospective study to evaluate drug use among pregnant women(Springer, 2019) Umar, Rashida Muhammad; Koçberber, Emine Karataş; Beşiroğlu, R.; Şahin, A. K.[Abstract Not Available]Öğe An artificial neural network design for determination of hashimoto's thyroiditis sub-groups(Central Bohemia University, 2016) Aktan, Mehmet Emin; Akdoğan, Erhan; Zengin, Namık; Güney, Ömer Faruk; Parlar, Rabia EdibeIn this study, an artificial neural network was developed for estimating Hashimoto's Thyroiditis subgroups. Medical analysis and measurements from 75 patients were used to determine the parameters most effective on disease sub-groups. The study used statistical analyses and an artificial neural network that was trained by the determined parameters. The neural network had four inputs: thyroid stimulating hormone, free thyroxine (fT4), right lobe size (RLS), and RLS2 - fT4(4), and two outputs for three groups: euthyroid, subclinical, and clinical. After training, the network was tested with data collected from 30 patients. Results show that, overall, the neural network estimated the sub-groups with 90% accuracy. Hence, the study showed that determination of Hashimoto's Thyroiditis sub-groups can be made via designed artificial neural network.Öğe The evaluation of phenytoin treatment according to the corrected phenytoin levels(Springer, 2016) Karataş Koçberber, Emine; Ceylan, Cengizhan; Kızılaslan, Deniz; Erdoğan, Cem; Berk, Barkın[Abstract Not Available]
