Botulinum toxin a augmentation of strabismus surgery for large-angle strabismus a retrospective case series and literature review

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dc.contributor.authorDikkaya Çiçek, Funda
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorKaraaslan, Nisa
dc.date.accessioned2026-04-17T12:59:38Z
dc.date.available2026-04-17T12:59:38Z
dc.date.issued2025
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.description.abstractPurpose: To report the results of botulinum toxin A (BTA)–augmented bilateral recession or monocular recession/resection surgery in a case series of patients with large-angle strabismus and review the relevant literature. Methods: This retrospective study reviewed the medical records of 24 patients treated with BTA-augmented strabismus surgery for large-angle horizontal strabismus (55 prism diopters or greater) with a minimum 6-month follow-up. Patients underwent unilateral recession-resection or bilateral rectus muscle recession surgery with intraoperative BTA injection into the recessed muscle(s). Main outcome measures were postoperative angle of deviation and success rate, defined as a final deviation of 10 prism diopters or less. Results: Of 24 patients (20 esotropia, 4 exotropia), the mean age was 9.2 years (range: 1 to 64 years). Mean preoperative deviation was 61.2 prism diopters for esotropia and 66.2 prism diopters for exotropia. Mean final postoperative deviation was 6.6 prism diopters for esotropia and 14.5 prism diopters for exotropia. Successful outcomes were achieved in 75% of patients with esotropia and 50% of patients with exotropia. Conclusions: BTA augmentation of conventional strabismus surgery dosages is a promising approach for managing large-angle strabismus, particularly esotropia. Optimal patient selection and follow-up are needed to maximize surgical success rates.
dc.identifier.citationDikkaya Çiçek, F., Karaman Erdur, S. ve Karaaslan, N. (2025). Botulinum toxin a augmentation of strabismus surgery for large-angle strabismus a retrospective case series and literature review. Journal of Pediatric Ophthalmology and Strabismus, 62(1), 5-11. http://dx.doi.org/10.3928/01913913-20240708-01
dc.identifier.doi10.3928/01913913-20240708-01
dc.identifier.endpage11
dc.identifier.issn0191-3913
dc.identifier.issn1938-2405
dc.identifier.issue1
dc.identifier.pmid39141768
dc.identifier.scopus2-s2.0-85216331495
dc.identifier.scopusqualityQ3
dc.identifier.startpage5
dc.identifier.urihttp://dx.doi.org/10.3928/01913913-20240708-01
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13440
dc.identifier.volume62
dc.identifier.wosWOS:001291819300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDikkaya Çiçek, Funda
dc.institutionauthorKaraman Erdur, Sevil
dc.institutionauthorid0000-0001-9829-7268
dc.institutionauthorid0009-0007-5755-3836
dc.language.isoen
dc.relation.ispartofJournal of Pediatric Ophthalmology and Strabismus
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdolescent
dc.subjectBotulinum Toxins
dc.subjectRetrospective Studies
dc.subjectReview
dc.titleBotulinum toxin a augmentation of strabismus surgery for large-angle strabismus a retrospective case series and literature review
dc.typeOther

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