Infection and guillain–barre syndrome – a lifelong relation

dc.authorid0000-0002-7919-1326
dc.contributor.authorZoubi, Magdi
dc.contributor.authorMahroum, Naim
dc.date.accessioned2024-05-15T10:48:05Z
dc.date.available2024-05-15T10:48:05Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractGuillain–Barre syndrome (GBS) is an autoimmune neurological disease considered as the most common cause of acute flaccid paralysis worldwide. In terms of etiology and pathogenesis, upper respiratory infection, gastroenteritis, and Zika virus are among the well-documented infections preceding the appearance of GBS. To what extent SARS-CoV-2 is involved in GBS is still controversial as will be explained later in this chapter. The first manifestations of GBS usually include progressive weakness of limbs accompanied by the absence of or reduced reflexes. Another presentation could be facial diplegia with paraesthesia or a pharyngeal–cervical–brachial manifestation. GBS is divided into various subtypes: acute axonal motor neuropathy (AMAN) and acute inflammatory demyelinating neuropathy (AIDP). Miller-Fisher syndrome and Bickerstaff brainstem encephalitis are subtypes that are clinically different from GBS but serologically similar to it. Miller-Fisher syndrome, characterized by ataxia, areflexia, and ophthalmoplegia, is considered to be a subtype of GBS, firstly because CSF examination of patients with Miller-Fisher syndrome revealed an albumin-cytologic dissociation and secondly some of the patients might develop GBS later in the clinical course of the disease.
dc.identifier.citationZoubi, M. ve Mahroum, N. (2024). Infection and guillain–barre syndrome – a lifelong relation. Infection and Autoimmunity içinde (949-961. ss.). Elsevier. http://dx.doi.org/10.1016/B978-0-323-99130-8.00046-5
dc.identifier.doi10.1016/B978-0-323-99130-8.00046-5
dc.identifier.endpage961
dc.identifier.isbn9780323991308
dc.identifier.isbn9780323991315
dc.identifier.scopus2-s2.0-85189605530
dc.identifier.scopusqualityN/A
dc.identifier.startpage949
dc.identifier.urihttp://dx.doi.org/10.1016/B978-0-323-99130-8.00046-5
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12457
dc.indekslendigikaynakScopus
dc.institutionauthorMahroum, Naim
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofInfection and Autoimmunityen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCampylobacter Jejuni
dc.subjectGuillain–Barre Syndrome
dc.subjectMycoplasma Pneumoniae
dc.subjectSARS-Cov-2
dc.titleInfection and guillain–barre syndrome – a lifelong relation
dc.typeBook Chapter

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