Physical and optical disectors

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dc.authorid0000-0002-6984-3079
dc.contributor.authorAltun, Gamze
dc.contributor.authorElamin, Abdalla Ahmed Eldaw
dc.contributor.authorKaplan, Arife Ahsen
dc.contributor.authorKipanyula, Maulilio J.
dc.contributor.authorKaya, Sefa Ersan
dc.contributor.authorKaplan, Süleyman
dc.date.accessioned2024-11-05T11:00:09Z
dc.date.available2024-11-05T11:00:09Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractIn morphometric studies, two-dimensional histological sections are evaluated using designbased stereological methods in order to obtain three-dimensional structural information about the tissue. The stereology is a combination of geometric measurements and statistical sampling principles. The basis of stereological applications is the idea that the samples selected for analysis represent the whole structure. One of the most critical parameters in any organ or tissue is "number." Numerical data in biological structures can be obtained using the "disector" method. This provides data concerning the numerical density of particles in three-dimensional structures and yields information about the structural and functional connections of the biological tissue in question. The disector method is applied in two ways: physical disector and optical disector. The physical disector method involves the examination of two consecutive sections, while consecutive thick sections are used in the optical disector method. Both methods employ an unbiased counting frame to ensure that each particle is counted only once. This chapter provides definitions of the physical disector and optical disector methods and discusses their application to light and electron microscopic images in detail.
dc.identifier.citationAltun, G., Elamin, A. A. E., Kaplan, A. A., Kipanyula, M. J., Kaya, S. E. ve Kaplan, S. (2024). Physical and optical disectors. A Manual of the Stereological Techniques içinde (51-76. ss.). Nova Science Publishers, Inc.
dc.identifier.endpage76
dc.identifier.isbn9798891138940
dc.identifier.isbn9798891137707
dc.identifier.scopus2-s2.0-85201356652
dc.identifier.scopusqualityN/A
dc.identifier.startpage51
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12859
dc.indekslendigikaynakScopus
dc.institutionauthorKaplan, Arife Ahsen
dc.language.isoen
dc.publisherNova Science Publishers, Inc.
dc.relation.ispartofA Manual of the Stereological Techniquesen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNeuroquantification
dc.subjectOptical Disector
dc.subjectPhysical Disector
dc.subjectStereology
dc.subjectUnbiased Counting Frame
dc.titlePhysical and optical disectors
dc.typeBook Chapter

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