Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women

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dc.authorid0000-0003-3302-5004
dc.authorid0000-0003-2923-5869
dc.contributor.authorKutlu, Pelin
dc.contributor.authorKarabulut, Seda
dc.contributor.authorKorkmaz, Oya
dc.date.accessioned2021-11-29T12:31:47Z
dc.date.available2021-11-29T12:31:47Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractObjective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure due to endometrial problems. A debate continues regarding the benefit of this technique because of the low number of evidence-based studies. Mechanism: Different PRP preparation methods have been described in the literature, aiming to obtain the highest number of platelets following centrifugation steps. Findings in brief : Research on the use of PRP in female infertility aims to improve the deteriorated hormonal profile, gamete production and implantation of the embryo into the endometrium. Conclusions: This paper reviewed literature evaluating the impact of PRP on the outcomes of subsequent ART cycles in infertile women. PRP is a safe and easy-to-apply procedure and can be used as an 'add-on' therapy in patients with reduced ovarian reserve, ovarian failure or implantation failure prior to the in vitro fertilization (IVF) cycle, although it is still regarded as an empirical treatment method. Further studies should be conducted to enlighten the subject.
dc.identifier.citationKutlu, P., Karabulut, S. ve Korkmaz, O. (2021). Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women. Clinical and Experimental Obstetrics and Gynecology, 48(5), 1025-1031. https://dx.doi.org/10.31083/j.ceog4805165
dc.identifier.doi10.31083/j.ceog4805165
dc.identifier.endpage1031
dc.identifier.issn0390-6663
dc.identifier.issn2709-0094
dc.identifier.issue5
dc.identifier.scopusqualityQ4
dc.identifier.startpage1025
dc.identifier.urihttps://dx.doi.org/10.31083/j.ceog4805165
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8588
dc.identifier.volume48
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherIMR Press
dc.relation.ispartofClinical and Experimental Obstetrics and Gynecologyen_US
dc.relation.publicationcategoryDiÄŸer
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectInfertility
dc.subjectIVF
dc.subjectPlatelet-Rich Plasma (PRP)
dc.subjectOvarian Failure
dc.titleAdministration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women
dc.typeReview Article

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