Phytochemical analysis, antioxidant, and enzyme inhibition activity of five Salvia taxa from Turkey

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dc.authorid0000-0002-6869-8703
dc.contributor.authorYılmaz, Gülderen
dc.contributor.authorEruygur, Nuraniye
dc.contributor.authorEkşi Bona, Gülnur
dc.contributor.authorBona, Mehmet
dc.contributor.authorAkdeniz, Mehmet
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorErtaş, Abdulselam
dc.date.accessioned2022-12-23T08:43:58Z
dc.date.available2022-12-23T08:43:58Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Botanik Ana Bilim Dalı
dc.description.abstractSalvia L. species are widely used for treatment of different disorders in traditional Turkish medicine. In this study, the methanol extracts of five Salvia taxa, including S. aucheri subsp. canescens, S. aytachii, S. heldreichiana, S. viridis, and S. wiedemannii were investigated for their antioxidant activity and enzyme inhibitory potentials which are related with health-benefit properties. In addition, total phenolic and flavonoid contents were determined with Folin- Ciocalteu and aluminum chloride spectrophotometric method, respectively. Screening of enzyme inhibition activity was performed out using ELISA microplate reader. Antioxidant activity was evaluated by 2,2?-diphenyl-1-picrylhydrazyl (DPPH) and 2,2? -Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging and iron chelating tests. The S. aytachii extract was found with highest total phenol content (77.82 ± 1.76 µg PE/mg) and total flavonoid content (22.33 ± 0.17 µg QE/mg) as dry weight basis. These findings specify that the investigated Salvia taxa for anticholinesterase activity can be appealed further phytochemical estimation for spotting its active components.
dc.identifier.citationYılmaz, G., Eruygur, N., Ekşi Bona, G., Bona, M., Akdeniz, M., Yılmaz, M. A. ... Ertaş, A. (2023). Phytochemical analysis, antioxidant, and enzyme inhibition activity of five Salvia taxa from Turkey. South African Journal of Botany, 152, 212-221. https://doi.org/10.1016/j.sajb.2022.11.027
dc.identifier.doi10.1016/j.sajb.2022.11.027
dc.identifier.endpage221
dc.identifier.issn0254-6299
dc.identifier.issn1727-9321
dc.identifier.scopus2-s2.0-85143974408
dc.identifier.scopusqualityQ2
dc.identifier.startpage212
dc.identifier.urihttps://doi.org/10.1016/j.sajb.2022.11.027
dc.identifier.urihttps://hdl.handle.net/20.500.12511/10172
dc.identifier.volume152
dc.identifier.wos000900063500006en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorEkşi Bona, Gülnur
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofSouth African Journal of Botanyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAntioxidant
dc.subjectEnzyme Inhibition
dc.subjectLC-MS/MS
dc.subjectPhytochemical
dc.subjectSalvia
dc.titlePhytochemical analysis, antioxidant, and enzyme inhibition activity of five Salvia taxa from Turkey
dc.typeArticle

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