The association between erectile dysfunction and subclinical hypothyroidism in males with type 2 diabetes mellitus

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dc.authorid0000-0003-0547-1883
dc.contributor.authorSivritepe, Rıdvan
dc.contributor.authorUçak Basat, Sema
dc.contributor.authorBaygül, Arzu
dc.contributor.authorBasat, Okcan
dc.date.accessioned2021-12-17T06:50:51Z
dc.date.available2021-12-17T06:50:51Z
dc.date.issued2021
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractAim: Overt hypothyroidism is known to affect sexual functions, but data on subclinical hypothyroidism (SCH) are insufficient. We aimed to investigate the relationship between erectile dysfunction (ED) and SCH in men with type 2 Diabetes Mellitus. Methods: This cross-sectional study included 117 diabetic patients aged between 45-70 years who applied to our outpatient clinic between March and June 2018. Biochemical blood tests and levels of hormones were analyzed. International erectile function index-5 (IIEF-5) questionnaire was applied for the assessment of ED. According to the IIEF-5 questionnaire scores, patients were grouped as severe ED (n=47), moderate ED (n=46), and no ED (n=24). Patients were also grouped according to the level of thyroid-stimulating hormone (TSH) into 3 groups; 0.27-2.49 mU/l (n=58), 2.5-4.2 mU/l (n=33), and >4.2 mU/l (n=26). Statistically significance level was set at 0.05. Results: 40% of the patients had severe ED and 39% moderate ED, while 21% had no ED. The TSH levels were significantly different between the ED groups (p<0.001). A significant negative correlation was found between the IIEF-5 score and the TSH levels (p<0.001, r=-0.453). The IIEF-5 score, and duration of ED were significantly different between the TSH groups (both; p<0.001). Conclusions: SCH is closely associated with ED in diabetic men. So, we recommend conducting thyroid function tests in diabetic men with ED and screening for ED in men with SCH.
dc.identifier.citationSivritepe, R., Uçak Basat, S., Baygül, A. ve Basat, O. (2021). The association between erectile dysfunction and subclinical hypothyroidism in males with type 2 diabetes mellitus. The Medical Bulletin of Haseki, 59(5), 411-418. https://dx.doi.org/10.4274/haseki.galenos.2021.7484
dc.identifier.doi10.4274/haseki.galenos.2021.7484
dc.identifier.endpage418
dc.identifier.issn1302-0072
dc.identifier.issn2147-2688
dc.identifier.issue5
dc.identifier.scopusqualityQ4
dc.identifier.startpage411
dc.identifier.trdizinid513437
dc.identifier.urihttps://dx.doi.org/10.4274/haseki.galenos.2021.7484
dc.identifier.urihttps://hdl.handle.net/20.500.12511/8689
dc.identifier.volume59
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publishing House
dc.relation.ispartofThe Medical Bulletin of Hasekien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiabetes Mellitus
dc.subjectErectile Dysfunction
dc.subjectHypothyroidism
dc.subjectMale
dc.subjectThyrotropin
dc.subjectType 2
dc.titleThe association between erectile dysfunction and subclinical hypothyroidism in males with type 2 diabetes mellitus
dc.typeArticle

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