The anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae)

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dc.authorid0000-0002-6869-8703
dc.contributor.authorAydın, Bilge
dc.contributor.authorYuca, Hafize
dc.contributor.authorKarakaya, Songül
dc.contributor.authorEkşi Bona, Gülnur
dc.contributor.authorGöger, Gamze
dc.contributor.authorTekman, Enes
dc.contributor.authorAcar Şahin, Aydan
dc.contributor.authorSytar, Oksana
dc.contributor.authorCivaş, Ayşe
dc.contributor.authorCanlı, Deniz
dc.contributor.authorPınar, Nur Münevver
dc.contributor.authorGüvenalp, Zuhal
dc.date.accessioned2023-09-14T11:25:30Z
dc.date.available2023-09-14T11:25:30Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalı
dc.description.abstractScilla siberica subsp. armena is known as Siberian Squill which is naturally distributed in Lebanon-Syria, Transcaucasus, and Turkey. It is a perennial bulbous plant with a short vegetation period from March to May. In this study, the antimicrobial, antioxidant, alpha-amylase, and alpha-glucosidase inhibitory activities of corm, leaf, and flower methanolic extracts were examined. The anatomy and morphology of the plant organs were investigated by light and electron microscopes. The anatomy of S. siberica subsp. armena was investigated for the first time by electron microscopy in this study. The corm, leaf, and flower methanolic extracts were assessed against E. coli ATCC 8739, S. aureus ATCC 6538, B. subtilis ATCC 19,659, C. albicans ATCC 10,231, C. krusei ATCC 14,243, and C. tropicalis ATCC 750. Among the extracts, that obtained from the blue pollen showed the best antimicrobial activity against C. tropicalis ATCC 750 strain with a MIC value of 312.5 mu g/mL. The highest phenolic content was determined in leaf extract with 53.59211 mu g GAE/mg extract value. The extract showed the best antilipid peroxidation activity with 376.69 mu g/mL value. Using DPPIT and ABTS(+) tests, it was determined that the flower and leaf extracts have the best activity (IC50 = 756.13 mu g/mL and IC50 = 94.07 mu g/mL, respectively). The flower extract exhibited a-glucosidase inhibitory activity with the IC50 value of 5239 mu g/mL. Based on the presented results of the in vitro antimicrobial, antioxidant, and antidiabetic activities of the S. siberica subsp. armena, we suggest that natural compounds from S. siberica subsp. armena are of potential use for the improvement of an antidiabetic, antioxidant, and antimicrobial agent.
dc.description.sponsorshipTürkiye Bilimsel ve Teknolojik Araştırma Kurumuen_US
dc.identifier.citationAydın, B., Yuca, H., Karakaya, S., Ekşi Bona, G., Göger, G., Tekman, E. ... Güvenalp, Z. (2023). The anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae). Protoplasma, 260(2), 371-389. https://dx.doi.org/10.1007/s00709-022-01784-9
dc.identifier.doi10.1007/s00709-022-01784-9
dc.identifier.endpage389
dc.identifier.issn0033-183X
dc.identifier.issn1615-6102
dc.identifier.issue2
dc.identifier.pmid35716225
dc.identifier.scopus2-s2.0-85132286512
dc.identifier.scopusqualityQ1
dc.identifier.startpage371
dc.identifier.urihttps://dx.doi.org/10.1007/s00709-022-01784-9
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11433
dc.identifier.volume260
dc.identifier.wos000812584100001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorEkşi Bona, Gülnur
dc.language.isoen
dc.publisherSpringer Wien
dc.relation.ispartofProtoplasmaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnatomy
dc.subjectAntidiabetic
dc.subjectAntimicrobial
dc.subjectAntioxidant
dc.subjectMorphology
dc.subjectScilla Siberica Subsp. Armena
dc.titleThe anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae)
dc.typeArticle

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