Effectiveness of tranexamic acid on bleeding in conization

dc.authorid0000-0002-1634-6781
dc.authorid0000-0002-7069-279X
dc.contributor.authorAlbayrak Denizli, Ayşe Betül
dc.contributor.authorBostancı Ergen, Evrim
dc.contributor.authorÖzdemir, Pelin
dc.contributor.authorAktaş, Özgür
dc.contributor.authorGiray, Burak
dc.contributor.authorKabaca Kocakuşak, Canan
dc.date.accessioned2023-06-13T07:42:37Z
dc.date.available2023-06-13T07:42:37Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: Bleeding is the most common complication of conization of cervix. Hemostatic sutures, intraoperative ferric subsulfate, or vasopressin can be used when intraoperative bleeding occurred, whereas oral tranexamic acid (TA) may be used for post-operative bleeding. In this study, we aimed to find out whether intraoperative cervical TA administration in patients undergoing conization caused changes in the amount of intraoperative bleeding and post-operative hemogram. Material and Methods: Patients who have undergone cervical conization between January 2019 and July 2019 in Zeynep Kamil Health Application and Research Center Gynecological Diseases and Birth Clinic were evaluated. One hundred and five patients were included to our study. One ampoule of 10% TA was applied cervically to 47 of these patients. Both groups were evaluated in terms of measuring the intraoperative amount of blood in the aspirator, changes in post-operative hb/htc/plt values compared to the pre-operative values, and the rate of post-operative bleeding. Results: In our study, the amount of intraoperative hemorrhage and pre-operative hemoglobin, hematocrit, and platelet values compared to the post-operative values were found to be similar in both groups. Conclusion: Although TA has been shown to be effective on hemorrhage in benign gynecologic operations, menorrhagia, and postpartum hemorrhages, no significant effect on hemorrhage in conization with cervical TA administration has been demonstrated.
dc.identifier.citationAlbayrak Denizli, A. B., Bostancı Ergen, E., Özdemir, P., Aktaş, Ö., Giray, B. ve Kabaca Kocakuşak, C. (2023). Effectiveness of tranexamic acid on bleeding in conization. Zeynep Kamil Medical Journal, 54(1), 12-16. https://doi.org/10.14744/zkmj.2022.62534
dc.identifier.doi10.14744/zkmj.2022.62534
dc.identifier.endpage16
dc.identifier.issn2757-8062
dc.identifier.issue1
dc.identifier.startpage12
dc.identifier.trdizinid1165070
dc.identifier.urihttps://doi.org/10.14744/zkmj.2022.62534
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11074
dc.identifier.volume54
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorBostancı Ergen, Evrim
dc.institutionauthorKabaca Kocakuşak, Canan
dc.language.isoen
dc.publisherKare Publishing
dc.relation.ispartofZeynep Kamil Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectCervical Cytology
dc.subjectCervical Intraepithelial Neoplasia
dc.subjectConization
dc.subjectHuman Papilloma Virus
dc.subjectTranexamic Acid
dc.titleEffectiveness of tranexamic acid on bleeding in conization
dc.typeArticle

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