Paroxysmal atrial fibrillation and related thromboembolism may be a hidden factor in the development of dementia

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dc.contributor.authorTokatlı, Alptuğ
dc.contributor.authorYiğiner, Ömer
dc.contributor.authorÖzmen, Namık
dc.contributor.authorUzun, Mehmet
dc.contributor.authorKılıçaslan, Fethi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:44Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:44Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000389140100007
dc.descriptionPubMed ID: 26781960
dc.description.abstractWe read the article entitled ‘Correlations between homocysteine and grey matter volume in patients with Alzheimer's disease’ by Park et al. with great interest.1 In this well?designed research, they used brain magnetic resonance imaging to demonstrate that increased serum homocysteine levels were not associated with a decreased volume of cerebral grey matter in patients with Alzheimer's disease. Park et al. excluded patients with cardiovascular disease and recruited only patients with Alzheimer's disease, not vascular dementia. However, among elderly individuals, it is too difficult to determine which patients have vascular disease according to their medical history. Although patients may not have experienced any vascular events or symptoms, age? related arteriosclerosis is often present in this age group. Furthermore, because of silent attacks, these patients often have undiagnosed episodes of paroxysmal atrial fibrillation (AF). The prevalence of AF was found to be 9% in individuals >80 years of age and 0.1% in subjects <55 years of age.2 These data were derived from trials in which diagnosis was based on a 12?lead electrocardiogram obtained during an office visit. AF is classified into three types based on episode duration: paroxysmal AF, persistent AF, and permanent AF.3 Although other types of AF can be easily diagnosed with a routine 12?lead electrocardiogram, paroxysmal AF may be overlooked. To determine whether paroxysmal AF attacks have occurred, ambulatory monitoring is required. Therefore, it is presumed that the real?world prevalence of AF is higher than that determined in trials.3
dc.identifier.citationTokatlı, A., Yiğiner, Ö., Özmen, N., Uzun, M. ve Kılıçaslan, F. (2016). Paroxysmal atrial fibrillation and related thromboembolism may be a hidden factor in the development of dementia. Psychogeriatrics, 16(6), 382-383. https://dx.doi.org/10.1111/psyg.12186
dc.identifier.doi10.1111/psyg.12186
dc.identifier.endpage383
dc.identifier.issn1346-3500
dc.identifier.issn1479-8301
dc.identifier.issue6
dc.identifier.scopusqualityQ2
dc.identifier.startpage382
dc.identifier.urihttps://dx.doi.org/10.1111/psyg.12186
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3721
dc.identifier.volume16
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPsychogeriatricsen_US
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectParoxysmal Atrial
dc.subjectFibrillation and Related
dc.subjectThromboembolism
dc.subjectDevelopment of Dementia
dc.titleParoxysmal atrial fibrillation and related thromboembolism may be a hidden factor in the development of dementia
dc.typeLetter

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