Reactivity of posterior cortical electroencephalographic alpha rythms during eyes opening in cognitively intact older adults and patients with dementia due to Alzheimer's and lewy diseases

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dc.authorid0000-0002-0860-0524
dc.contributor.authorLopez, S.
dc.contributor.authorBabiloni, C.
dc.contributor.authorNoce, G.
dc.contributor.authorTucci, F.
dc.contributor.authorLizio, R.
dc.contributor.authorFerri, R.
dc.contributor.authorSoricelli, A.
dc.contributor.authordel Percio, C.
dc.date.accessioned2023-09-11T09:13:36Z
dc.date.available2023-09-11T09:13:36Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.description.abstractIntroduction: Patients with Lewy Bodies (DLB) and Parkinson’s disease dementia (PDD) suffer from vigilance dysregulation reflected by hypersomnolence, cognitive fluctuations, hallucinations, and sleep disorders. Therefore, we hypothesized that such dysregulation may be reflected by altered reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the vigilance transition from eyes-closed to -open condition. More specifically, we tested whether the above mentioned reactivity of posterior rsEEG alpha rhythms may differ in patients with DLB, PDD and Alzheimer’s disease (ADD) dementia, as a functional probe of the dominant cortical neural synchronization mechanisms regulating the vigilance in posterior visual systems. Methods: In two different studies, we extracted clinical, demographical, and rsEEG datasets in (1) older adults (Healthy, N=28) seniors as well as matched DLB (N=42) and ADD (N=48) patients, and (2) 25 Healthy seniors as well as matched PDD (N=73) and ADD (N=35) patients, from an international Eurasian database. The eLORETA freeware was used to estimate cortical rsEEG sources at delta, theta, alpha, beta, and gamma frequency bands during eye-closed and eye-open conditions.
dc.identifier.citationLopez, S., Babiloni, C., Noce, G., Tucci, F., Lizio, R., Ferri, R. ... del Percio, C. (2023). Reactivity of posterior cortical electroencephalographic alpha rythms during eyes opening in cognitively intact older adults and patients with dementia due to Alzheimer's and lewy diseases. International Journal of Psychophysiology içinde (26-27. ss.). https://dx.doi.org/10.1016/j.ijpsycho.2023.05.065
dc.identifier.doi10.1016/j.ijpsycho.2023.05.065
dc.identifier.endpage27
dc.identifier.issn0167-8760
dc.identifier.issn1872-7697
dc.identifier.issueSupplement: S
dc.identifier.startpage26
dc.identifier.urihttps://dx.doi.org/10.1016/j.ijpsycho.2023.05.065
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11403
dc.identifier.volume188
dc.identifier.wos001037996300065en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.institutionauthorGüntekin, Bahar
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofInternational Journal of Psychophysiologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAlzheimer's
dc.subjectLewy Diseases
dc.subjectOlder Adults
dc.subjectElectroencephalographic Alpha Rythms
dc.titleReactivity of posterior cortical electroencephalographic alpha rythms during eyes opening in cognitively intact older adults and patients with dementia due to Alzheimer's and lewy diseases
dc.typeConference Object

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