Synthesis and characterization of novel oxime derivatives

Basit Öğe Kaydı
dc.contributor.authorArslan, Taner
dc.contributor.authorKeskin, Serhat
dc.contributor.authorDemirayak, Şeref
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:39Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:39Z
dc.date.issued2016
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalı
dc.descriptionWOS: 000391709300008
dc.description.abstractBackground: The synthesis of effective drugs are very important for the scientist. The various biological effects of the thiazole, oxime and ether functional groups are well known properties by the drug developers. So we have synthesised new molecules which contains three of them on the same molecules. Methods: The acetophenone derivatives have been used for synthesis new oximes. The synthetic pathway includes mainly four steps. sl. alpha-Bromination of acetophenone derivatives, s2. Synthesis of thiazole ring using brominated acetophenones, s3. Synthesis of ethers using synthesised thiazole, s4. Synthesis of oximes. Results: The synthesised molecules characterised using IR, I H-NMR, 13C-NMR and elementel analysis methods. Conclusion: The new oximes which include thiazole and ether groups have been synthesised using acetophenone derivatives.
dc.description.sponsorshipEskiehir Osmangazi Uni.Research Project Comm. [200819034]en_US
dc.description.sponsorshipThis paper supported by Eskiehir Osmangazi Uni.Research Project Comm. with 200819034 project number.en_US
dc.identifier.citationArslan, T., Keskin, S. ve Demirayak, Ş. (2016). Synthesis and characterization of novel oxime derivatives. Bentham Science Publ Ltd, 13(9), 672-677. https://dx.doi.org/10.2174/1570178613666161017111615
dc.identifier.doi10.2174/1570178613666161017111615
dc.identifier.endpage677
dc.identifier.issn1570-1786
dc.identifier.issn1875-6255
dc.identifier.issue9
dc.identifier.scopusqualityQ2
dc.identifier.startpage672
dc.identifier.urihttps://dx.doi.org/10.2174/1570178613666161017111615
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3385
dc.identifier.volume13
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBentham Science Publ Ltd
dc.relation.ispartofLetters In Organic Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectThiazole
dc.subjectOxime
dc.subjectEther
dc.titleSynthesis and characterization of novel oxime derivatives
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Demirayak-Seref 2016.pdf
Boyut:
386.94 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Eczacılık Fakültesi Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu