Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives

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dc.contributor.authorSoroush, Alborz
dc.contributor.authorPourhossein, Siavash
dc.contributor.authorHosseingholizadeh, Dorrin
dc.contributor.authorHjazi, Ahmed
dc.contributor.authorShahhosseini, Reza
dc.contributor.authorKermanshahi, Nazgol
dc.contributor.authorBehnamrad, Parisa
dc.contributor.authorGhavamikia, Nima
dc.contributor.authorDadashpour, Mehdi
dc.date.accessioned2024-05-27T07:27:25Z
dc.date.available2024-05-27T07:27:25Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi
dc.description.abstractPlant-derived immunomodulators and antitumor factors have appealed lots of attention from natural product scientists for their efficiency and safety and their important contribution to well-designed targeted drug action and delivery mechanisms. Zerumbone (ZER), the chief component of Zingiber zerumbet rhizomes, has been examined for its wide-spectrum in the treatment of multi-targeted diseases. The rhizomes have been used as food flavoring agents in numerous cuisines and in flora medication. Numerous in vivo and in vitro experiments have prepared confirmation of ZER as a potent immunomodulator as well as a potential anti-tumor agent. This review is an interesting compilation of all the important results of the research carried out to date to investigate the immunomodulatory and anticancer properties of ZER. The ultimate goal of this comprehensive review is to supply updated information and a crucial evaluation on ZER, including its chemistry and immunomodulating and antitumour properties, which may be of principal importance to supply a novel pathway for subsequent investigation to discover new agents to treat cancers and immune-related sickness. In addition, updated information on the toxicology of ZER has been summarized to support its safety profile.
dc.description.sponsorshipCancer Research Center, Semnan University of Medical Sciences, Semnan, Iran.en_US
dc.identifier.citationSoroush, A., Pourhossein, S., Hosseingholizadeh, D., Hjazi, A., Shahhosseini, R., Kavoosi, H. ... Dadashpour, M. (2024). Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives. Medical Oncology, 41(5). http://dx.doi.org/10.1007/s12032-024-02327-3
dc.identifier.doi10.1007/s12032-024-02327-3
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue5
dc.identifier.pmid38652207
dc.identifier.scopus2-s2.0-85191039168
dc.identifier.scopusqualityQ2
dc.identifier.urihttp://dx.doi.org/10.1007/s12032-024-02327-3
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12505
dc.identifier.volume41
dc.identifier.wos001207150600005en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorShahhosseini, Reza
dc.language.isoen
dc.relation.ispartofMedical Oncologyen_US
dc.relation.publicationcategoryDiÄŸer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnti-Tumor
dc.subjectGlioma
dc.subjectImmunomodulators
dc.subjectZerumbone
dc.titleAnti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives
dc.typeOther

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