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Öğe Lhermitte-Duclos disease with orthostatic hypotension(Turkish Neurological Society, 2016) Helvacı Yılmaz, Nesrin; Şeker, Mehmet; Omaygenç, Mehmet Onur; Yaka, Umut; Eryiğit, Nazan; Yuluğ, BurakLhermitte-Duclos disease is a rare cerebellar dysplastic gangliocytoma. The most common symptoms include headache, nausea, vomiting, blurred vision, and imbalance. The typical appearance on cranial magnetic resonance imaging is hyper-intensity on T2-weighted images and hypo-intensity on T1-weighted images. The disease generally presents with benign progress. Development of obstructive hydrocephalus is an indication for urgent surgical intervention and surgery outcomes are satisfactory. Orthostatic hypotension is a very rare clinical presentation of this syndrome and ours is the second case of orthostatic hypotension to be reported in the literature.Öğe Persistent sciatalgia due to a wandering bipolar forceps tip after posterior lumbar stabilization: A case report(Georg Thıeme Verlag Kg, 2016) Gömleksiz, Cengiz; Tokmak, Mehmet; Yaka, Umut; Arslan, Erhan; Özbek, Muhammed Arif; Albayrak, Serdar BakiThere are several reports in the literature about the retained surgical materials as a cause of radicular pain or sensory impairment after spinal surgery. We report a patient with a persistent radicular pain in the distribution of left S1 nerve dermatome following lumbar stabilization surgery. Retained bipolar forceps tip has not been reported previously in the literature as a cause of sciatalgia after posterior lumbar surgery.Öğe The axon protective effects of syringic acid on ischemia/ereperfusion injury in a rat sciatic nerve model(Turkish Neurosurgical Society, 2017) Tokmak, Mehmet; Şehitoğlu, Müserref Hilal; Yüksel, Yasemin; Güven, Mustafa; Akman, Tarık; Aras, Adem Bozkurt; Yaka, Umut; Gömleksiz, Cengiz; Albayrak, Serdar Baki; Coşar, MuratAIM: In the relevant literature, there is no experimental study that investigated the axon protective effects of syringic acid- a polyphenol compound- with an anti-oxidant capacity on ischemia/reperfusion injury. MATERIAL and METHODS: The rats were randomly divided into four groups: Control group (no medication or surgical procedure), Sham group, Syringic acid group, and Methyprednisolone (MP) Group. lschemia was achieved by abdominal aorta clamping and all animals were sacrificed 24 hours after ischemia. Harvested sciatic nerve segments were investigated histopathologically and for tissue biochemistry. RESULTS: lschemic fiber degeneration scores were found significantly lower in syringic acid and MP groups than sham group. Additionally, apoptosis-related cysteine peptidase caspase-3 immunostaining scores were lower in syringic acid and MP groups. Biochemically, superoxide dismutase and nuclear respiratory factor 1 values were significantly higher in syringic acid group compared to those of control and sham groups while malondialdehyde levels were significantly lower in the syringic acid group. CONCLUSION: Syringic acid reduces oxidative stress and axonal degeneration in rat sciatic nerve after ischemia/reperfusion injury. Therefore, syringic acid may play a role in the treatment of peripheral nerve injuries due to ischemia/reperfusion.











