dc.contributor.author | Çelik, İstemi Han | |
dc.contributor.author | Demirel, Gamze | |
dc.contributor.author | Uraş, Nurdan | |
dc.contributor.author | Oǧuz, Şerife Suna | |
dc.contributor.author | Erdeve, Ömer | |
dc.contributor.author | Dílmen, Uǧur | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:35:32Z | |
dc.date.available | 10.07.201910:49:14 | |
dc.date.available | 2019-07-10T19:35:32Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Çelik, İ. H., Demirel, G., Uraş, N., Oǧuz, Ş. S., Erdeve, Ö., ve Dilmen, U. (2015). The role of serum interleukin-6 and C-reactive protein levels for differentiating aetiology of neonatal sepsis. Archivos Argentinos de Pediatria, 113(6), 534-537. https://dx.doi.org/10.5546/aap.2015.eng.534 | en_US |
dc.identifier.issn | 0325-0075 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/833 | |
dc.identifier.uri | https://dx.doi.org/10.5546/aap.2015.eng.534 | |
dc.description.abstract | Introduction: In our clinical practice, we observed high interleukin-6 (IL-6) levels in gram-negative sepsis. Objective: To investigate the relationship between IL-6 and C-reactive protein (CRP) levels and early determination of neonatal sepsis of gram-negative or gram-positive aetiology. Population and Methods: White blood cell count, IL-6 and CRP levels were compared among different groups. Results: Gram-negative, gram-positive and fungal infection groups consisted of 73, 82 and 15 patients, respectively. The optimal cut-off levels of IL-6 between gram-negative and gram-positive fungal infection groups were 202 and 57 pg/ ml. The fungal infection group had higher CRP levels than gram-negative and positive infection groups. Conclusions: To our knowledge, this is the largest reported study aiming at determining of IL-6 cut-off levels to differentiate neonatal sepsis aetiology. Gram-negative microorganisms led to 10 fold higher IL-6 production. The evaluation of IL-6 and CRP is useful to diagnose and also differentiate neonatal sepsis aetiology. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Sociedad Argentina de Pediatria | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Newborn | en_US |
dc.subject | Sepsis | en_US |
dc.subject | Interleukin-6 | en_US |
dc.subject | C-reactive Protein | en_US |
dc.subject | Gramnegative Infections | en_US |
dc.subject | Fungal Disease | en_US |
dc.title | The role of serum interleukin-6 and C-reactive protein levels for differentiating aetiology of neonatal sepsis | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Archivos Argentinos de Pediatria | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.identifier.volume | 113 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 534 | en_US |
dc.identifier.endpage | 537 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.5546/aap.2015.eng.534 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q3 | en_US |