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dc.contributor.authorÇelik, İstemi Han
dc.contributor.authorDemirel, Gamze
dc.contributor.authorUraş, Nurdan
dc.contributor.authorOǧuz, Şerife Suna
dc.contributor.authorErdeve, Ömer
dc.contributor.authorDílmen, Uǧur
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:35:32Z
dc.date.available10.07.201910:49:14
dc.date.available2019-07-10T19:35:32Z
dc.date.issued2015
dc.identifier.citationÇelik, İ. H., Demirel, G., Uraş, N., Oǧuz, Ş. S., Erdeve, Ö., ve Dilmen, U. (2015). The role of serum interleukin-6 and C-reactive protein levels for differentiating aetiology of neonatal sepsis. Archivos Argentinos de Pediatria, 113(6), 534-537. https://dx.doi.org/10.5546/aap.2015.eng.534en_US
dc.identifier.issn0325-0075
dc.identifier.urihttps://hdl.handle.net/20.500.12511/833
dc.identifier.urihttps://dx.doi.org/10.5546/aap.2015.eng.534
dc.description.abstractIntroduction: In our clinical practice, we observed high interleukin-6 (IL-6) levels in gram-negative sepsis. Objective: To investigate the relationship between IL-6 and C-reactive protein (CRP) levels and early determination of neonatal sepsis of gram-negative or gram-positive aetiology. Population and Methods: White blood cell count, IL-6 and CRP levels were compared among different groups. Results: Gram-negative, gram-positive and fungal infection groups consisted of 73, 82 and 15 patients, respectively. The optimal cut-off levels of IL-6 between gram-negative and gram-positive fungal infection groups were 202 and 57 pg/ ml. The fungal infection group had higher CRP levels than gram-negative and positive infection groups. Conclusions: To our knowledge, this is the largest reported study aiming at determining of IL-6 cut-off levels to differentiate neonatal sepsis aetiology. Gram-negative microorganisms led to 10 fold higher IL-6 production. The evaluation of IL-6 and CRP is useful to diagnose and also differentiate neonatal sepsis aetiology.en_US
dc.language.isoengen_US
dc.publisherSociedad Argentina de Pediatriaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNewbornen_US
dc.subjectSepsisen_US
dc.subjectInterleukin-6en_US
dc.subjectC-reactive Proteinen_US
dc.subjectGramnegative Infectionsen_US
dc.subjectFungal Diseaseen_US
dc.titleThe role of serum interleukin-6 and C-reactive protein levels for differentiating aetiology of neonatal sepsisen_US
dc.typearticleen_US
dc.relation.ispartofArchivos Argentinos de Pediatriaen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.identifier.volume113en_US
dc.identifier.issue6en_US
dc.identifier.startpage534en_US
dc.identifier.endpage537en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.5546/aap.2015.eng.534en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ3en_US


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