Show simple item record

dc.contributor.authorKaradağ, Ayşe Esra
dc.contributor.authorÇaşkurlu, Ayşegül
dc.contributor.authorOkur, Mehmet Evren
dc.contributor.authorGüzelmeriç, Etil
dc.contributor.authorÜstündağ Okur, Neslihan
dc.contributor.authorTosun, Fatma
dc.contributor.authorYeşilada, Erdem
dc.contributor.authorDemirci, Fatih
dc.date.accessioned2021-04-12T11:26:47Z
dc.date.available2021-04-12T11:26:47Z
dc.date.issued2021en_US
dc.identifier.citationKaradağ, A. E., Çaşkurlu, A., Okur, M. E., Güzelmeriç, E., Üstündağ Okur, N., Tosun, F. ... Demirci, F. (2021). Hemostatic activity of cistus creticus extract in wistar albino rats. Revista Brasileira de Farmacognosia, 30(6), 844-847. https://dx.doi.org/10.1007/s43450-020-00120-7en_US
dc.identifier.issn1981-528X
dc.identifier.issn0102-695X
dc.identifier.urihttps://dx.doi.org/10.1007/s43450-020-00120-7
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6722
dc.description.abstractAerial part preparations of Cistus creticus L., Cistaceae, are traditionally used in Anatolia as a hemostatic agent. The air-dried aerial parts were extracted with methanol. Gels were prepared, followed by the hemostatic activity evaluation using Wistar albino rats in vivo tail tip amputation model. The chemical characterization of the total extract was performed by high-performance thin-layer chromatography. The methanol extract was loaded to a hydrogel base to complete a concentration of 2.5 and 7.5%. As a result, the 2.5% extract gel was found more effective on both bleeding time and amount. Hyperoside and tiliroside, which may be the components responsible for the hemostatic properties of the analyzed plant material, were dereplicated as major constituents.en_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHPTLCen_US
dc.subjectTopical Applicationen_US
dc.subjectBlood Stopperen_US
dc.subjectCoagulating Activityen_US
dc.subjectFlavonoid Glycosideen_US
dc.subjectTail Bleedingen_US
dc.titleHemostatic activity of cistus creticus extract in wistar albino ratsen_US
dc.typearticleen_US
dc.relation.journalRevista Brasileira de Farmacognosiaen_US
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalıen_US
dc.authorid0000-0002-3412-0807en_US
dc.authorid0000-0001-7277-920Xen_US
dc.authorid0000-0003-2533-5141en_US
dc.identifier.volume30en_US
dc.identifier.issue6en_US
dc.identifier.startpage844en_US
dc.identifier.endpage847en_US
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/1139B411801272
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s43450-020-00120-7en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record