Yazar "Akgül Çağlar, Tuba" için Makale Koleksiyonu listeleme
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Complexities of the chemogenetic toolkit: Differential mDAAO activation by D-amino substrates and subcellular targeting
Erdoğan, Yusuf Can; Altun, Hamza Yusuf; Seçilmiş, Melike; Ata, Büşra N.; Sevimli, Gülşah; Çokluk, Zeynep; Zaki, Asal Ghaffari; Sezen, Serap; Akgül Çağlar, Tuba; Sevgen, İlker; Steinhorn, Benjamin; Ai, Huiwang; Öztürk, Gürkan; Belousov, Vsevelod V.; Michel, Thomas; Eroğlu, Emrah (Elsevier Inc., 2021)A common approach to investigate oxidant-regulated intracellular pathways is to add exogenous H2O2 to living cells or tissues. However, the addition of H2O2 to the culture medium of cells or tissues approach does not ... -
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
Koç, Arzuhan; Şahoğlu Göktaş, Sevilay; Akgül Çağlar, Tuba; Çağavi, Esra (Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ... -
Development of a chemogenetic approach to manipulate intracellular pH
Zaki, Asal Ghaffari; Miri, Seyed Mohammad; Çimen, Şeyma; Akgül Çağlar, Tuba; Yiğit, Esra Nur; Aydın, Mehmet S.; Öztürk, Gürkan; Eroğlu, Emrah (American Chemical Society, 2023)Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ... -
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
Akgül Çağlar, Tuba; Durdu, Zeynep Begüm; Turhan, M. U.; Günal, Mehmet Yalçın; Aydın, Mehmet Şerif; Öztürk, Gürkan; Çağavi, Esra (Elsevier, 2021)The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ... -
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels
Sevimli, Gülşah; Smith, Matthew J.; Akgül Çağlar, Tuba; Bilir, Şükriye; Seçilmiş, Melike; Altun, Hamza Y.; Yiğit, Esra N.; Yang, Fan; Keeley, Thomas P.; Malli, Roland; Öztürk, Gürkan; Mann, Giovanni E.; Eroğlu, Emrah (Elsevier B.V., 2022)Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation ... -
Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering
Aydemir Sezer, Ümran; Öztürk Yavuz, Kevser; Örs, Gizem; Bay, Sadık; Aru, Başak; Söğüt, Oğuz; Akgül Çağlar, Tuba; Bozkurt, Mehmet Recep; Çağavi, Esra; Yanıkkaya Demirel, Gülderen; Sezer, Serdar; Karaca, Hüseyin (Wiley, 2020)Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral ...