WoS Q Kategorisi "Q4" Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü (SABİTA) İçin Listeleme
Toplam kayıt 20, listelenen: 1-20
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Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
Biological evaluation of imidazopyridine derivatives as potential anticancer agents against breast cancer cells
(Springer, 2022)Imidazo[1,2-a]pyridine cores have increasing importance in the pharmaceutical industry with their wide range pharmacological activities. In this study, two series of imidazopyridine derivatives were synthesized. It was ... -
Blood viscosity and inflammation in first-episode and acute exacerbations of schizophrenia: A case-control study with healthy controls
(Turkish Neuropsychiatric Society, 2023)Introduction: Elevated proinflammatory status and alterations in blood flow, both of which are associated with the pathophysiology of schizophrenia, may be linked with an increased risk of cardiovascular diseases. However, ... -
Corrosion behavior of Ni–Fe–Mo deposits obtained under different electrodeposition conditions
(Springer, 2021)Ternary Ni-Fe-Mo coatings have been proposed for anti-corrosion applications to replace chromium coating. To analyze the effects of deposition current and duration six different Ni-Fe-Mo films have been electrodeposited ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell
(Springer, 2023)Background: Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
Determination of antioxidant, anticancer, antidiabetic and antimicrobial activities of Turkish red pine (Pinus brutia Ten.) bark ultrasound-assisted extract as a functional food additive
(Akademiai Kiado Zrt., 2023)Turkish red pine (Pinus brutia Ten.) is an important tree species that grows widely in Turkiye. In this study, Box-Behnken experimental design was created and optimised for ultrasound assisted extraction of bioactive ... -
DLPF targeted repetitive transcranial magnetic stimulation improves brain glucose metabolism along with the clinical and electrophysiological parameters in CBD patients
(Bentham Science Publishers, 2022)Background: Corticobasal Degeneration (CBD) is a rare neurological disease caused by the pathological accumulation of tau protein. The primary pathological features of CBD include progressive neurodegenerative processes ... -
Event-related delta and theta responses may reflect the valence discrimination in the emotional oddball task
(Springer Science and Business Media Deutschland GmbH, 2023)How emotion and cognition interact is still a matter of debate. Investigation of this interaction in terms of the brain oscillatory dynamics appears to be an essential approach. To investigate this topic, we designed two ... -
Gamma-amino butyric acid immunoreactivity in the testis tissue of wistar and genetic absence epilepsy rats
(Soc Chilena Anatomia, 2021)Studies have shown the adverse effects of epileptic seizures on reproductive health. The aim of the present study was to investigate morphological changes, apoptosis and GABA localization in the testis tissue of genetic ... -
IL13 fused pseudomonas exotoxin targets various cancers in vitro
(International Institute of Anticancer Research, 2021)Background/Aim: Pseudomonas exotoxin (PE) is one of the most widely used toxins in the construction of therapeutic fusion proteins in pre-clinical studies followed by phase trials. In principle, PE acts by blocking protein ... -
Integrin α5β1 mediated cellular reorganization in human mesenchymal stem cells during neuronal differentiation
(International Institute of Anticancer Research, 2021)Background/Aim: Mesenchymal stem cells (MSCs) have been widely used for yielding neurons in culture to study nervous system pathologies and develop regenerative approaches. In this study, cellular rearrangements of human ... -
Laurocerasus officinalis Roem. fruit extract induces cell death through caspase mediated apoptosis in gastric cancer cell lines
(Walter de Gruyter GmbH, 2021)Objectives: Laurocerasus officinalis Roem. fruits are traditionally used for several health problems. Although there are some studies about its antiproliferative effects on different cancer cells, no study was reported ... -
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
(SAGE Publications Inc, 2023)The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ... -
Neuropsychiatric outcomes and caregiver distress in primary progressive aphasia
(Wiley, 2023)Background: In this study, we aimed to outline the neuropsychiatric consequences of primary progressive aphasia (PPA) and to understand how neuropsychiatric symptomatology affects distress in caregivers. Methods: The ... -
A novel autosomal recessive candidate gene responsible for rasopathy-like phenotype and bone marrow failure: rasa3
(2024)Although many genetic etiologies, such as Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis congenita, and Diamond-Blackfan anemia, from hereditary bone marrow failure are known today, the responsible gene remains ... -
Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
(NLM (Medline), 2020)Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood ... -
Quantitative evaluation of brain volumes in drug-free major depressive disorder using MRI-Cloud method
(Lippincott Williams & Wilkins, 2021)Background Quantitative analysis of the high-resolution T1-weighted images provides useful markers to measure anatomical changes during brain degeneration related to major depressive disorder (MDD). However, there are ... -
The role of circadian rhythm in the regulation of cellular protein profiles in the brain
(The Scientific and Technological Research Council of Turkey, 2021)Background/aim: Circadian rhythm plays a significant role in the regulation of almost all kinds of physiological processes. In addition, it may also have a direct or indirect effect on the neurodegenerative processes, ... -
Striatal dopaminergic neurons as a potential target for GDNF based ischemic stroke therapy
(Turkey Clinics, 2022)Background/aim: Glial cell-line-derived neurotrophic factor (GDNF) is a well-known regulatory neurotrophic factor on dopaminergic neurons. Several pathologies have been documented so far in case of any impairment in the ... -
Synthesis of novel oxadiazole derivatives and their cytotoxic activity against various cancer cell lines
(TUBITAK, 2022)Caffeic acid (CA), ferulic acid (FA) and caffeic acid phenethyl ester (CAPE) have a broad anticancer effect on various cell lines. In this study, nine ferulic and caffeic acid-based 1,2,4 and 1,3,4 oxadiazole molecular ...