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Toplam kayıt 10, listelenen: 1-10
Reaktif oksijen türleri ve obezitede oksidatif stres
(Marmara Üniversitesi, 2015)
Obezite; alınan enerjinin, harcanan enerjiden fazla olmasından kaynaklanan, tüm dünyada prevalansı endişe verici şekilde artan kronik bir hastalıktır. Obeziteye neden olan etkenlerden biri olan oksidatif stres, reaktif ...
Advanced oxidation protein products and ischaemia-modified albumin in obstructive sleep apnea
(Wiley-Blackwell, 2014)
BackgroundSeveral studies have shown that obstructive sleep apnea increases incidence of cardiovascular morbidity and mortality. The high systemic oxidative stress in obstructive sleep apnea has been considered as a major ...
Modulation of oxidative stress and Ca2+ mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum
(Pergamon-Elsevier Science Ltd., 2014)
A main component of St. John's Wort (Hypericum perforatum, HP) is hyperforin which has antioxidant properties in dorsal root ganglion (DRG) neurons, due to its ability to modulate NADPH oxidase and protein kinase C. Recent ...
Efficacy of statins on sirtuin 1 and endothelial nitric oxide synthase expression: The role of sirtuin 1 gene variants in human coronary atherosclerosis
(Wiley, 2015)
Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and are used to reduce the risk of coronary artery disease (CAD) due to their pleiotropic effects. Recently, greater focus has been placed on the role ...
Evaluation of apoptotic molecular pathways for smooth muscle cells isolated from thoracic aortic aneurysms in response to oxidized sterols
(Springer, 2014)
Oxysterols, oxygenated derivatives of cholesterol, are found abundantly in the plasma and atherosclerotic plaques, a common risk factor for thoracic aortic aneurysms (TAAs). Among the oxysterols, namely 7-ketocholesterol ...
Assessment of relationship between serum vascular adhesion protein-1 (VAP-1) and gestational diabetes mellitus
(Taylor & Francis Ltd., 2019)
Purpose: VAP-1 plays a crucial role in inflammation, oxidative stress and endothelial dysfunction which are main pathophysiologic mechanisms for gestational diabetes. We aimed to determine serum VAP-1 levels, assess its ...
Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia
(Pergamon Elsevier Science Ltd, 2018)
Sirtuins have gained considerable attention as epigenetic regulators for slowing aging and age-related disorders. The growing association between neurodegeneration and inflammation has led researchers to investigate ...
Maternal serum sestrin 2 levels in preeclampsia and their relationship with the severity of the disease
(Taylor & Francis Inc, 2019)
Objective: To investigate sestrin 2 (SESN2) levels in preeclampsia (PE) cases and uncomplicated pregnancies. Methods: Cross-sectional study including 26 pregnant women with PE, 24 with severe-PE, and 30 randomly selected ...
Evaluation of thiol/disulfide homeostasis in patients with pityriasis rosea
(Taylor and Francis Ltd., 2019)
Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous ...
Postacute effects of kisspeptin-10 on neuronal injury induced by L-methionine in rats
(Wiley-Blackwell, 2014)
Apart from its effect on the regulation of reproductive function, recent studies indicate that kisspeptin may play roles in the antioxidant defense system. The antioxidant defense system and oxidative stress contribute to ...