Bölüm "İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü, Farmasötik Teknoloji Ana Bilim Dalı" PubMed İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 18, listelenen: 1-18
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An alternative approach to wound healing field; New composite films from natural polymers for Mupirocin dermal delivery
(Elsevier, 2019)In this study, novel adhesive films were prepared for Mupirocin dermal delivery. Natural polymers as chitosan, sodium alginate and carbopol were used for films development to evaluate possible interactions and drug release ... -
Assessment of aprotinin loaded microemulsion formulations for parenteral drug delivery: Preparation, characterization, in vitro release and cytotoxicity studies
(Bentham Science, 2016)The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ... -
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
(Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Chitosan modification-enhanced silencing effect of Ad5-shPDGF-D vector in breast cancer cell line MDA-MB-231
(Bentham Science Publishers, 2023)Background: Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because ... -
Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine
(Elsevier B.V., 2023)Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to extensive first-pass metabolism and is ... -
Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-beta reveals anticancer effect in breast cancer
(Wiley, 2023)Background: Platelet derived growth factors (PDGF)-D and the expression of its receptor increase in neoplastic progression of cancer. Co-silencing of growth factor and receptor can be suggested as an important strategy for ... -
CORRECTION to: Clinical and demographic characteristics and two-year efficacy and safety data of 508 multiple sclerosis patients with fingolimod treatment (Archives of Neuropysychiatry, 60, 23)
(Turkish Neuropsychiatric Society, 2023)The name of the author Gökçe Sözer was mistakenly written as Gökçe Sezer. The correct name and institution are as follows. -
Current status of mucoadhesive gel systems for buccal drug delivery
(Bentham Science Publishers Ltd, 2021)Background: Buccal drug delivery is a fascinating research field. Gel-based formulations present potent characteristics as buccal systems since they have great physicochemical properties. Methods: Among the various gels, ... -
Effect of microemulsion formulation on biodistribution of Tc-99m-Aprotinin in acute pancreatitis models induced rats
(Taylor & Francis, 2016)Background: Aprotinin is a monomeric globular polypeptide, which derived from bovine lung tissue and theoretically attractive molecule in ameliorating the effects of acute pancreatitis. Acute pancreatitis is an inflammatory ... -
Evaluation of the effect of honey-containing chitosan/hyaluronic acid hydrogels on wound healing
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)The 3D polymeric network structure of hydrogels imitates the extracellular matrix, thereby facilitating cell growth and differentiation. In the current study, chitosan/hyaluronic acid/honey coacervate hydrogels were produced ... -
Hypertension in 2017: Update in treatment and pharmaceutical innovations
(Bentham Science Publishers, 2017)Hypertension can be referred to as modern scourge in 2017 and although, it seems that an improvement has been done during the passage of time, the full treatment still remains an unmet achievement for clinicians. Hypertension ... -
Investigation of antimicrobial activities of some herbs containing essential oils and their mouthwash formulations
(Turkish Pharmacists Association, 2018)Objectives: The aim of this study was to prepare pharmaceutical formulations of mouthwashes and to examine the antimicrobial activities of essential oils obtained from plants used traditionally in Turkey for oral infections. ... -
New therapeutic system based on hydrogels for vaginal candidiasis management: Formulation-characterization andin vitroevaluation based on vaginal irritation and direct contact test
(Taylor and Francis Ltd., 2020)The objective of the present research was to examine the possible usage of terbinafine loaded hydrogels for vaginal application as part of vaginal candidiasis treatment. Vaginal candidiasis belongs to the most frequent ... -
Novel microemulsion containing benzocaine and fusidic acid simultaneously: Formulation, characterization, and in vitro evaluation for wound healing
(Springer Science and Business Media Deutschland GmbH, 2024)Modern drug carrier technologies, such as microemulsions with small droplet sizes and high surface areas, improve the ability of low water solubility active ingredients to permeate and localize. The goal of this study was ... -
Novel sprayable thermosensitive benzydamine hydrogels for topical application: Development, characterization, and in vitro biological activities
(Springer Science and Business Media Deutschland GmbH, 2023)Benzydamine hydrochloride (BZD) having analgesic, anesthetic, and anti-inflammatory effects is used orally or topically in the treatment of disorders such as joint inflammation and muscle pain. Within the scope of this ... -
Ophthalmic applications of SLN and NLC
(Bentham Science Publishers Ltd., 2017)Background: The eyes are among the most readily accessible organs in terms of location in the body, yet drug delivery to eye tissues is particularly problematic. The anatomy, physiology and biochemistry of the eye limit ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
(Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ... -
Two different approaches for oral administration of voriconazole loaded formulations: Electrospun fibers versus beta-cyclodextrin complexes
(MDPI, 2016)In this work, a comparison between two different preparation methods for the improvement of dissolution rate of an antifungal agent is presented. Poly(epsilon-caprolactone) (PCL) electrospun fibers and beta-cyclodextrin ...