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Toplam kayıt 7, listelenen: 1-7
Phosphodiesterase 10A is a critical target for neuroprotection in a mouse model of ischemic stroke
(Springer, 2022)
Phosphodiesterase 10A (PDE10A) hydrolyzes adenosine 3 ',5 '-cyclic monophosphate (cAMP) and guanosine 3 ',5 '-cyclic monophosphate (cGMP). It is highly expressed in the striatum. Recent evidence implied that PDE10A may be ...
Systemic proteasome inhibition induces sustained post-stroke neurological recovery and neuroprotection via mechanisms involving reversal of peripheral immunosuppression and preservation of blood-brain-barrier integrity
(Springer, 2016)
In view of its profound effect on cell survival and function, the modulation of the ubiquitin-proteasome-system has recently been shown to promote neurological recovery and brain remodeling after focal cerebral ischemia. ...
Blood viscosity and inflammatory indices in treatment-resistant schizophrenia: A retrospective cross-sectional study
(Kare Publishing, 2023)
Objective: Alterations in blood flow and inflammation may be associated with the treatment response of psychotic disorders. However, changes in blood viscosity in patients with treatment-resistant schizophrenia (TRS) have ...
Evaluating the clinical significance of diazepam binding inhibitor in alzheimer's disease: A comparison with inflammatory, oxidative, and neurodegenerative biomarkers
(Karger, 2023)
Introduction: Alzheimer's disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor for ...
Blood viscosity and inflammation in first-episode and acute exacerbations of schizophrenia: A case-control study with healthy controls
(Turkish Neuropsychiatric Society, 2023)
Introduction: Elevated proinflammatory status and alterations in blood flow, both of which are associated with the pathophysiology of schizophrenia, may be linked with an increased risk of cardiovascular diseases. However, ...
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury
(John Wiley and Sons Inc, 2024)
A novel curcumin formulation increases relative absorption by 46 times (CurcuWIN®) of the total curcuminoids over the unformulated standard curcumin form. However, the exact mechanisms by which curcumin demonstrates its ...
The investigation of inflammation in drug-naive first-episode mania by measuring ferritin, peripheral inflammatory markers, and their ratios
(Istanbul University, 2024)
Objective: Bipolar disorder (BD) is a complex psychiatric disorder with a multifactorial etiology involving both genetic and environmental factors. Increased inflammatory parameters have been shown in previous studies in ...