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Dual action of exosomes derived from in vitro A beta toxicity model: The role of age for pathological response
(Elsevier Ireland Ltd, 2023)
Exosomes released from different cell types of the central nervous system play an essential role in the patho-genesis of Alzheimer's disease (AD). In this study, we aimed to create an animal model by injecting exosomes ...
Integrated multi-omics analyses of microbial communities: A review of the current state and future directions
(Royal Society of Chemistry, 2023)
Integrated multi-omics analyses of microbiomes have become increasingly common in recent years as the emerging omics technologies provide an unprecedented opportunity to better understand the structural and functional ...
TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1
(BioMed Central Ltd, 2024)
Background: T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid ...
Functional neural networks stratify Parkinson's disease patients across the spectrum of cognitive impairment
(Wiley, 2024)
Introduction Cognitive impairment (CI) is a significant non-motor symptoms in Parkinson's disease (PD) that often precedes the emergence of motor symptoms by several years. Patients with PD hypothetically progress from ...
Bioactive peptides: An alternative therapeutic approach for cancer management
(Frontiers Media SA, 2024)
Cancer is still considered a lethal disease worldwide and the patients’ quality of life is affected by major side effects of the treatments including post-surgery complications, chemo-, and radiation therapy. Recently, new ...
Plasma leptin, nesfatin 1, NPY, and zinc levels in obese and metabolic syndrome children
(Pera Yayincilik Hizmetleri, 2023)
Objective: The aim of this study is to investigate the relationship between leptin, nesfatin 1 and NPY hormones and zinc in boys and girls diagnosed with metabolic syndrome and obesity.
Methods: This study included a ...
Effects of pinealectomy and melatonin application on Serum Melatonin, Nesfatin-1 and ghrelin levels
(Pera Publishing Services, 2023)
Objective: In this study, it was aimed to investigate the relationship between the pineal gland and ghrelin and nesfatin-1 hormones in rats.
Methods: A total of 36 male rats were used in the study, and the animals were ...
Dietary zinc status in offspring of pregnant rats fed on a zinc-deficient diet is associated with Serum Albumin, Ast, and Alt levels
(Pera Publishing Services, 2023)
Objective: This study was carried out to investigate whether dietary zinc status is associated with serum albumin, AST and ALT levels in male offspring of mother rats fed a zinc deficient diet.
Methods: The study was ...
The investigation of inflammation in drug-naive first-episode mania by measuring ferritin, peripheral inflammatory markers, and their ratios
(Istanbul University, 2024)
Objective: Bipolar disorder (BD) is a complex psychiatric disorder with a multifactorial etiology involving both genetic and environmental factors. Increased inflammatory parameters have been shown in previous studies in ...