Ara
Toplam kayıt 21, listelenen: 1-10
A multi-spectral myelin annotation tool for machine learning based myelin quantification [version 1; peer review: 1 not approved]
(F1000 Research Ltd, 2021)
Myelin is an essential component of the nervous system and myelin damage causes demyelination diseases. Myelin is a sheet of oligodendrocyte membrane wrapped around the neuronal axon. In the fluorescent images, experts ...
Lithium modulates miR-1906 levels of mesenchymal stem cell-derived extracellular vesicles contributing to poststroke neuroprotection by toll-like receptor 4 regulation
(Wiley, 2021)
Lithium is neuroprotective in preclinical stroke models. In addition to that, poststroke neuroregeneration is stimulated upon transplantation of mesenchymal stem cells (MSCs). Preconditioning of MSCs with lithium further ...
Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei
(Elsevier Science Inc, 2021)
The study described here examined the effects of cavitation nuclei characteristics on histotripsy. Highspeed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ...
Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target
(American Society for Biochemistry and Molecular Biology Inc., 2021)
Hexokinase (HK) catalyzes the first step in glucose metabolism, making it an exciting target for the inhibition of tumor initiation and progression due to their elevated glucose metabolism. The upregulation of hexokinase-2 ...
Effect of salvianolic acid B on new bone formation in the orthopedically expanded suture: A histological and immunohistochemical study
(E H Angle Education Research Foundation, Inc., 2021)
Objectives: To determine the effects of Salvianolic acid B (Sal B) on new bone formation in the orthopedically expanded premaxillary sutures in rats.Materials and Methods: The sample consisting of Sprague Dawley rats (male, ...
Integrin α5β1 mediated cellular reorganization in human mesenchymal stem cells during neuronal differentiation
(International Institute of Anticancer Research, 2021)
Background/Aim: Mesenchymal stem cells (MSCs) have been widely used for yielding neurons in culture to study nervous system pathologies and develop regenerative approaches. In this study, cellular rearrangements of human ...
Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-beta/Smad2/3 pathway
(Springer Nature, 2021)
Systemic transplantation of oxygen-glucose deprivation (OGD)-preconditioned primary microglia enhances neurological recovery in rodent stroke models, albeit the underlying mechanisms have not been sufficiently addressed. ...
A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
(Nature Research, 2021)
Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ...
Adult mouse dorsal root ganglia neurons form aberrant glutamatergic connections in dissociated cultures
(Public Library of Science, 2021)
Cultured sensory neurons can exhibit complex activity patterns following stimulation in terms of increased excitability and interconnected responses of multiple neurons. Although these complex activity patterns suggest a ...
Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro
(John Wiley and Sons Inc, 2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), one of the most challenging global pandemics of the modern era. Potential treatment strategies against ...