ORCID "0000-0002-7199-583X" Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) için listeleme
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Cardiac immunology: A new era for immune cells in the heart
Koç, Arzuhan; Çağavi, Esra (Plenum Press, 2021)The immune system is essential for the development and homeostasis of the human body. Our current understanding of the immune system on disease pathogenesis has drastically expanded over the last decade with the definition ... -
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
Koç, Arzuhan; Şahoğlu Göktaş, Sevilay; Akgül Çağlar, Tuba; Çağavi, Esra (Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ... -
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
Akgül Çağlar, Tuba; Durdu, Zeynep Begüm; Turhan, M. U.; Günal, Mehmet Yalçın; Aydın, Mehmet Şerif; Öztürk, Gürkan; Çağavi, Esra (Elsevier, 2021)The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ... -
Experimental data of labeling the heart and cardiac cultures with a retrograde tracer in vitro and in vivo
Akgül Çağlar, Tuba; Günal, Mehmet Yalçın; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Elsevier Inc., 2021)Retrograde dyes are often used in basic research to investigate neuronal innervations of an organ. This article describes the experimental data on the application of retrograde dyes on the mouse heart in vivo and on the ... -
High-resolution mapping of sensory fibers at the healthy and post-myocardial infarct whole transgenic hearts
Göktaş Şahoğlu, Sevilay; Kazcı, Yusuf Enes; Karadoğan, Behnaz; Aydın, Mehmet Şerif; Nebol, Aylin; Turhan, Mehmet Uğurcan; Öztürk, Gürkan; Çağavi, Esra (Wiley, 2023)The sensory nervous system is critical to maintain cardiac function. As opposed to efferent innervation, less is known about cardiac afferents. For this, we mapped the VGLUT2-expressing cardiac afferent fibers of spinal ... -
Human macrophages directly modulate iPSC-derived cardiomyocytes at healthy state and congenital arrhythmia model in vitro
Koç, Arzuhan; Akdeniz, Celal; Çağavi, Esra (Springer Heidelberg, 2022)The electrophysiological regulation of cardiomyocytes (CMs) by the cardiac macrophages (M Phi s) has been recently described as an unconventional role of M Phi s in the murine heart. Investigating the molecular and ... -
Replating protocol for human induced pluripotent stem cell–derived cardiomyocytes
Koç, Arzuhan; Çağavi, Esra (Humana Press Inc., 2022)Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational cardiac research. Obtaining hiPSC-CM culture as a single-cell, monolayer or three-dimensional ... -
Revealing nervous and cardiac system interactions by iPSC-Based platforms
Mutlu Burnaz, Özlem; Çağavi, Esra (Elsevier, 2022)Cardiac function is regulated by the autonomic nervous system. In exchange, the sensorial information from the heart is relayed to the brain via sensory neurons as a crucial modulatory feedback mechanism. Cardiovascular ... -
Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering
Aydemir Sezer, Ümran; Öztürk Yavuz, Kevser; Örs, Gizem; Bay, Sadık; Aru, Başak; Söğüt, Oğuz; Akgül Çağlar, Tuba; Bozkurt, Mehmet Recep; Çağavi, Esra; Yanıkkaya Demirel, Gülderen; Sezer, Serdar; Karaca, Hüseyin (Wiley, 2020)Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral ...