Başlık için Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER) listeleme
Toplam kayıt 368, listelenen: 312-331
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Resting-state electroencephalographic delta rhythms may reflect global cortical arousal in healthy old seniors and patients with Alzheimer's disease dementia
(Elsevier, 2020)Extending Basar's theory of event-related EEG oscillations, here we hypothesize that even in quiet wakefulness, transient increases in delta rhythms may enhance global cortical arousal as revealed by the desynchronization ... -
Resting-state fMRI analysis in apathetic Alzheimer's disease
(AVES, 2020)PURPOSEDiagnosis of comorbid psychiatric conditions are a significant determinant for the prognosis of neurodegenerative diseases. Apathy, which is a behavioral executive dysfunction, frequently accompanies Alzheimer's ... -
Revealing nervous and cardiac system interactions by iPSC-Based platforms
(Elsevier, 2022)Cardiac function is regulated by the autonomic nervous system. In exchange, the sensorial information from the heart is relayed to the brain via sensory neurons as a crucial modulatory feedback mechanism. Cardiovascular ... -
The rhythmicity of life: A review of the circadian clocks
(Begell House Inc., 2021)Physiology of the mammalian body has been adapted to diurnal cycles of around 24 h, an evolutionary situation that affects a wide spectrum of biological events including sleep-to-wake transitions, feeding/fasting, body ... -
Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish
(Taylor & Francis Ltd, 2022)Among the mechanisms underlying Parkinson’s disease, many pathogenic mechanisms are suggested to be effective such as oxidative stress, mitochondrial dysfunction, disruption of the ubiquitin-proteasome system, and ... -
The role of circadian rhythm in the regulation of cellular protein profiles in the brain
(The Scientific and Technological Research Council of Turkey, 2021)Background/aim: Circadian rhythm plays a significant role in the regulation of almost all kinds of physiological processes. In addition, it may also have a direct or indirect effect on the neurodegenerative processes, ... -
Role of erythropoietin and its receptor in the development of endometriosis in rats
(Galenos Yayıncılık, 2019)Objective: Besides its hematopoietic function, erythropoietin (EPO) may protect tissues from degenerative disorders. As such, EPO and its receptors were revealed in nonhematopoietic cells, including stromal and endometrial ... -
The savant syndrome: a gift or a disability? A deeper look into metabolic correlates of hidden cognitive capacity
(Bentham Science Publishers, 2023)Savant syndrome is a rare and unusual condition that occurs in the presence of severe developmental disabilities, disorders, and injuries. The syndrome can be congenital from birth to childhood or acquired as a result of ... -
Science-inspired sustainable behavior
(American Association for the Advancement of Science, 2019)We asked young scientists this question: How has your awareness of science inspired you to adopt more sustainable and environmentally friendly behavior? Respondents from around the world described scientifi c concepts, ... -
Skov-3 over kanseri hücre hattında fotodinamik terapi uygulaması
(2017)Sürdürülen sayısız araştırmaya ve geliştirilen ilaçlara rağmen günümüzde kanser hala milyonlarca insanın ölümüne neden olan hastalıkların başında gelmektedir. Over kanseri en ölümcül kanserlerden biri olup kadınlarda en ... -
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
(Elife Sciences Publications Ltd, 2019)Comparative analyses of neuronal phenotypes in closely related species can shed light on neuronal changes occurring during evolution. The study of post-mortem brains of nonhuman primates (NHPs) has been limited and often ... -
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
(Tubitak Scientific & Technical Research Council Turkey, 2019)The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ... -
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
(American Society for Microbiology, 2022)Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ... -
Striatal dopaminergic neurons as a potential target for GDNF based ischemic stroke therapy
(Turkey Clinics, 2022)Background/aim: Glial cell-line-derived neurotrophic factor (GDNF) is a well-known regulatory neurotrophic factor on dopaminergic neurons. Several pathologies have been documented so far in case of any impairment in the ... -
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia
(NLM (Medline), 2022)Inflammation triggers secondary brain damage after stroke. The meninges and other CNS border compartments serve as invasion sites for leukocyte influx into the brain thus promoting tissue damage after stroke. However, the ... -
A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients
(John Wiley and Sons Inc, 2023)In Alzheimer's disease (AD), structural and functional changes in the brain may give rise to disruption of specific cognitive functions. The aim of this study is to investigate the functional connectivity alterations in ...
