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Toplam kayıt 22, listelenen: 1-10
Nanokorlar: Tanı ve tedaviye yönelik antikor fragmanları
(2018)
Nanokorlar, bilinen en küçük ve fonksiyonel antikor fragmanlarıdır. Yapısında sadece iki ağır zincir bulunduran antikorların (heavy chain only antibodies; HcAb) antijen bağlama bölgesi, “nanokor” (nanobody) olarak ...
Kafeinin ağırlık yönetimine etkileri
(Bülent Ecevit Üniversitesi Obezite ve Diyabet Uygulama ve Araştırma Merkezi, 2022)
Tüm dünyada büyük bir hızla artan obezite, ciddi bir halk sağlığı sorunu haline gelmiştir. Salgın boyutundaki bu sorunla mücadele etmek için güvenli, yaygın olarak bulunan ve uygun fiyatlı obezite karşıtı stratejilere ...
Protein and gene delivery systems for neurodegenerative disorders: Where do we stand today?
(MDPI, 2022)
It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’ lives. To date, there has not been an approved pharmacological ...
Nanoplasmonic biosensors: Theory, structure, design, and review of recent applications
(Elsevier, 2021)
Nanoplasmonic biosensing shows an immense potential to satisfy the needs of the global health industry -low-cost, fast, and portable automated systems; highly sensitive and real-time detection; multiplexing and miniaturization. ...
Chemogenetic tools for causal cellular and neuronal biology
(American Physiological Society, 2018)
Chemogenetic technologies enable selective pharmacological control of specific cell populations. An increasing number of approaches have been developed that modulate different signaling pathways. Selective pharmacological ...
Chemogenetic approaches to dissect the role of H2O2 in redox-dependent pathways using genetically encoded biosensors
(Portland Press Ltd, 2022)
Chemogenetic tools are recombinant enzymes that can be targeted to specific organelles and tissues. The provision or removal of the enzyme substrate permits control of its biochemical activities. Yeast-derived enzyme D-amino ...
EEG measures for clinical research in major vascular cognitive impairment: recommendations by an expert panel
(Elsevier Inc., 2021)
Vascular contribution to cognitive impairment (VCI) and dementia is related to etiologies that may affect the neurophysiological mechanisms regulating brain arousal and generating electroencephalographic (EEG) activity. A ...
Mesenchymal stem cell applications in polycystic ovary syndrome treatment
(Ondokuz Mayıs Üniversitesi, 2021)
Mesenchymal stem cells (MSCs) are highly capable of self-renewal and differentiation. They can be isolated from a variety of sources such as adipose tissue, bone marrow, umbilical cord, tooth pulp and can be cultured under ...
Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts
(Elsevier Ireland Ltd., 2020)
Alzheimer's disease (AD) is the most common neurodegenerative disease among the elderly with a progressive decline in cognitive function significantly affecting quality of life. Both the prevalence and emotional and financial ...
Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke
(NLM (Medline), 2020)
Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood ...