ORCID "0000-0003-2776-5807" Rektörlüğe Bağlı Birimler için listeleme
-
Bioconjugated beta-cyclodextrin-perfluorohexane nanocone clusters as functional nanoparticles for nanoparticle-mediated histotripsy
Toydemir, Cemran; Hall, Sarah; Demirel, Erhan; Elmacı, Dilşah Nur; Göl, Deniz; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin (American Chemical Society, 2022)Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs). NCCs can be obtained by simply mixing ... -
Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei
Edsall, Connor; Khan, Zerin Mahzabin; Mancia, Lauren; Hall, Sarah; Mustafa, Waleed; Johnsen, Eric; Klibanov, Alexander L.; Yüksel Durmaz, Yasemin; Vlaisavljevich, Eli (Elsevier Science Inc, 2021)The study described here examined the effects of cavitation nuclei characteristics on histotripsy. Highspeed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ... -
Development of acoustically active nanocones using the host-guest interaction as a new histotripsy agent
Rehman, Tanzeel Ur; Khirallah, Jennifer; Demirel, Erhan; Howell, Justin; Vlaisavljevich, Eli; Yüksel Durmaz, Yasemin (American Chemical Society, 2019)Histotripsy is a noninvasive and nonthermal ultrasound ablation technique, which mechanically ablates the tissues using very short, focused, high-pressured ultrasound pulses to generate dense cavitating bubble cloud. ... -
Effective PEGylation method to improve biocompatibility of graphene derivatives
Demirel, Erhan; Karaca, Ezgi; Yüksel Durmaz, Yasemin (Elsevier, 2020)The research on the use of graphene (G) in the biological applications has increased exponentially with emerging concerns regarding its biosafety and potential cytotoxicity. The modification of the surface with biocompatible ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
Kaymaz, Betül; Mustafa, Waleed; Hall, Sarah; Vlaisavljevich, Eli; Şensoy, Özge; Yüksel Durmaz, Yasemin (American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Nanoparticle-mediated histotripsy (NMH) using perfluorohexane 'nanocones'
Khirallah, Jennifer; Schmieley, Rebecca; Demirel, Erhan; Ur Rehman, Tanzeel; Howell, Justin; Yüksel Durmaz, Yasemin; Vlaisavljevich, Eli (Institute of Physics Publishing, 2019)Nanoparticle-mediated histotripsy (NMH) is an ultrasound treatment strategy that combines acoustically sensitive nanoparticles with histotripsy. Previous NMH studies using perfluorocarbon (PFC) nanodroplets (ND's), ∼200 ... -
Nanoparticle-mediated histotripsy using dual-frequency pulsing methods
Edsall, Connor; Huynh, Laura; Mustafa, Waleed; Hall, Timothy L.; Yüksel Durmaz, Yasemin; Vlaisavljevich, Eli (2024)Objective: Nanoparticle-mediated histotripsy (NMH) is a novel ablation method that combines nanoparticles as artificial cavitation nuclei with focused ultrasound pulsing to achieve targeted, non-invasive, and cell-selective ... -
A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media
Altınkök, Çağatay; Sağdıç, Gökhan; Dağlar, Özgün; Ercan Ayra, Merve; Yüksel Durmaz, Yasemin; Durmaz, Hakan; Açık, Gökhan (Elsevier Ltd, 2023)Phosphorylated poly(vinyl chloride) (PPVC)/polyethyleneimine (PEI)-based nanofibers were produced via electrospinning in their blended solutions for the first time. For this purpose, PVC was partially converted into PVC-N3 ... -
PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery
Demirel, Erhan; Yüksel Durmaz, Yasemin (Elsevier Ltd, 2023)Combination therapies involving anticancer drugs and gene therapy agents have become a potential treatment for different cancer types reducing the side effects of anticancer drugs while enhancing their effectiveness. Here, ...