ORCID "0000-0003-4292-5717" Rektörlüğe Bağlı Birimler için listeleme
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Does sleep disturbance affect the amyloid clearance mechanisms in Alzheimer's disease?
Yuluğ, Burak; Hanoğlu, Lütfü; Kılıç, Ertuğrul (Wiley, 2017)Sleep is an important factor that plays a key role in Alzheimer's disease pathogenesis. However, it is still unclear whether poor-quality sleep may overlap with sleep disturbances in the underlying dysfunctional mechanisms ... -
The effect of rifampicin on the neuronal cell survival in primary cortical neuron culture after laser axotomy
Ozansoy, Mehmet; Coşkun, Ebru; Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Günal, Mehmet Yalçın; Bayraktaroğlu, Zübeyir; Yuluğ, Burak; Hanoğlu, Lütfü (2019)Aim: Neurodegeneration caused by the axonal injury is a widely seen phenomenon in spinal cord and traumatic brain injuries. Due to the disintegration of the synaptic connection neurotrophic factors could not be transported ... -
The effects of repetitive transcranial magnetic stimulation and aerobic exercise on cognition, balance and functional brain networks in patients with Alzheimer's disease
Budak, Miray; Bayraktaroğlu, Zübeyir; Hanoğlu, Lütfü (Springer, 2023)The purpose of this study was to investigate the effects of high-frequency repetitive Transcranial Magnetic Stimulation (rTMS) and aerobic exercises (AE) in addition to the pharmacological therapy (PT) in Alzheimer's Disease ... -
Electrophysiological evidence of altered facial expressions recognition in Alzheimer's disease: A comprehensive ERP study
Fide, Ezgi; Ekmek Savaş, Derya Durusu; Aktürk, Tuba; Güntekin, Bahar; Hanoğlu, Lütfü; Yener, Görsev G. (Elsevier Ireland Ltd, 2019)Objectives: The present study aims to evaluate the amplitude and latency of event-related potentials (ERPs) P100, N170, VPP and N230 in individuals with Alzheimer's disease (AD) compared to healthy elderly controls, using ... -
Enhancing memory capacity by experimentally slowing theta frequency oscillations using combined EEG-tACS
Aktürk, Tuba; de Graaf, Tom A.; Güntekin, Bahar; Hanoğlu, Lütfü; Sack, Alexander T. (Nature Portfolio, 2022)he coupling of gamma oscillation (similar to 40+ Hz) amplitude to the phase of ongoing theta (similar to 6 Hz) oscillations has been proposed to be directly relevant for memory performance. Current theories suggest that ... -
FDG-PET scanning shows distributed changes in cortical activity associated with visual hallucinations in eye disease
Hanoğlu, Lütfü; Yıldız, Sultan; Çakır, Tansel; Hanoğlu, Taha; Yuluğ, Burak (Bentham Science Publ Ltd, 2019)Background and Objective: Charles Bonnet Syndrome (CBS) has been defined as complex visual hallucinations (CVH) due to visual loss. The underlying mechanism of CBS is not clear and the underlying pathophysiology of the ... -
fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing
Yaman, Handan; Yılmaz, Oğuz; Hanoğlu, Lütfü; Bayazıt, Yıldırım (Wiley, 2023)ObjectivesCoronavirus disease-2019 due to SARS-CoV-2 infection has been associated with neurological and neuropsychiatric illnesses as well as auditory system problems. In this study, we aimed to evaluate the impact of ... -
Functional neural networks stratify Parkinson's disease patients across the spectrum of cognitive impairment
Hajebrahimi, Farzin; Budak, Miray; Sarıcaoğlu, Mevhibe; Temel, Zeynep; Kahraman Demir, Tuğçe; Hanoğlu, Lütfü; Yıldırım, Süleyman; Bayraktaroğlu, Zübeyir (Wiley, 2024)Introduction Cognitive impairment (CI) is a significant non-motor symptoms in Parkinson's disease (PD) that often precedes the emergence of motor symptoms by several years. Patients with PD hypothetically progress from ... -
Impairment in recognition of emotional facial expressions in Alzheimer's disease is represented by EEG theta and alpha responses
Güntekin, Bahar; Hanoǧlu, Lütfü; Aktürk, Tuba; Ruşen, Ece; Yıldırım, Ebru; Yener, Görsev (Blackwell Publishing Inc., 2019)Behavioral studies have shown that the recognition of facial expressions may be impaired in patients with Alzheimer's disease (AD). The identification and recognition of a facial expression might be represented by event-related ... -
Left lateral parietal rTMS improves cognition and modulates resting brain connectivity in patients with Alzheimer's disease: Possible role of BDNF and oxidative stress
Velioğlu, Halil Aziz; Hanoğlu, Lütfü; Bayraktaroğlu, Zübeyir; Toprak, Güven; Güler, Eray Metin; Bektay, Muhammed Yunus; Mutlu Burnaz, Özlem; Yuluğ, Burak (Academic Press Inc., 2021)Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation technique which is increasingly used for cognitive impairment in Alzheimer?s Disease (AD). Although rTMS has been shown to modify ... -
Low frequency oscillations during hand laterality judgment task with and without personal perspectives: a preliminary study
Dilek, Burcu; Yıldırım, Ebru; Hanoğlu, Lütfü (Springer, 2023)Sense of personal perspective is crucial for understanding in attentional mechanisms of the perception in "self" or "other's" body. In a hand laterality judgment (HLJ) task, perception of perspective can be assessed by ... -
Metaproteogenomic analysis of saliva samples from Parkinson's disease patients with cognitive impairment
Arıkan, Muzaffer; Kahraman Demir, Tuğçe; Yıldız, Zeynep; Nalbantoğlu, Özkan Ufuk; Korkmaz, Nur Damla; Helvacı Yılmaz, Nesrin; Şen, Aysu; Özcan, Mutlu; Muth, Thilo; Hanoğlu, Lütfü; Yıldırım, Süleyman (Nature Portfolio, 2023)Cognitive impairment (CI) is very common in patients with Parkinson's Disease (PD) and progressively develops on a spectrum from mild cognitive impairment (PD-MCI) to full dementia (PDD). Identification of PD patients at ... -
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
Yuluğ, Burak; Ozansoy, Mehmet; Alökten, Merve; Çetin Ozansoy, Muzaffer Beyza; Çankaya, Şeyda; Hanoğlu, Lütfü; Kılıç, Ülkan; Kılıç, Ertuğrul (2020)Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ... -
The multifactorial role of pre-supplementary motor area stimulation in the freezing of gait: An alternative strategy to the classical drug-Target approach
Sarıcaoğlu, Mevhibe; Hanoğlu, Lütfü; Toprak, Güven; Helvacı Yılmaz, Nesrin; Yuluğ, Burak (Bentham Science Publishers, 2022)Introduction: The pre-supplementary motor area (Pre-SMA) plays a pivotal role in the control of voluntary motor control and freezing of gait (FOG) pathophysiological mechanism. Here, we aimed to modulate if the pre-SMA ... -
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
Hanoğlu, Lütfü; Velioğlu, Halil Aziz; Hanoğlu, Taha; Yuluğ, Burak (SAGE Publications Inc, 2023)The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ... -
The neuroprotective effect of focused ultrasound: New perspectives on an old tool
Yuluğ, Burak; Hanoğlu, Lütfü; Kılıç, Ertuğrul (Pergamon-Elsevier Science Ltd., 2017)Introduction Transcranial focused ultrasound (tFUS) is a novel technique that can noninvasively modulate the cortical function. Moreover, there are rapidly replicating evidence suggesting the role of tFUS for targeted ... -
Paracetamol alters empathy scores in healthy and headache subjects: Functional MRI correlates
Çankaya, Şeyda; Özdemir Öktem, Ece; Saatçi, Özlem; Velioğlu, Halil Aziz; Uygur, Abdullah Burak; Özşimşek, Ahmet; Hanoğlu, Lütfü; Yuluğ, Burak (Elsevier Science Ltd., 2020)Introduction: Although previous evidence suggest that paracetamol decreases psychological reactivity in healthy subjects, there is still no confirmed correlation between the empathy scores and brain activity in healthy and ... -
Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
Babiloni, Claudio; Noce, Giuseppe; Tucci, Federico; Jakhar, Dharmendra; Ferri, Raffaele; Panerai, Simonetta; Catania, Valentina; Soricelli, Andrea; del Percio, Claudio (Elsevier Inc., 2024)Here, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease ... -
Power spectral density and coherence analysis of eye disease with and without visual hallucination
Yıldız, Sultan; Yuluğ, Burak; Kocabora, Mehmet Selim; Hanoğlu, Lütfü (Elsevier Ireland Ltd, 2021)Objectives: Charles Bonnet Syndrome (CBS) is a rare clinical condition which has been defined as complex visual hallucinations (CVH) due to visual loss. This study investigated differences in the EEG power spectral density ... -
Predicting the effects of repetitive transcranial magnetic stimulation on cognitive functions in patients with alzheimer's disease by automated EEG analysis
Kayasandık, Cihan Bilge; Velioğlu, Halil Aziz; Hanoğlu, Lütfü (Frontiers Media SA, 2022)Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that generally affects the elderly. Today, after the limited benefit of the pharmacological treatment strategies, numerous noninvasive brain ...