Ara
Toplam kayıt 38, listelenen: 11-20
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)
Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ...
Cytotoxicity of standardized curcuminoids mixture against epithelial ovarian cancer cell line SKOV-3
(MDPI, 2020)
Herbal medicine has been in use for centuries for a wide variety of ailments; however, the efficacy of its therapeutic agents in modern medicine is currently being studied. Curcuminoids are an example of natural agents, ...
The role of positive and negative pressure on cavitation nucleation in nanodroplet-mediated histotripsy
(Iop Publishing Ltd, 2016)
Nanodroplet-mediated histotripsy (NMH) is an ultrasound ablation technique combining histotripsy with acoustically sensitive perfluorocarbon (PFC) nanodroplets that can be selectively delivered to tumor cells for targeted ...
Development of acoustically active nanocones using the host-guest interaction as a new histotripsy agent
(American Chemical Society, 2019)
Histotripsy is a noninvasive and nonthermal ultrasound ablation technique, which mechanically ablates the tissues using very short, focused, high-pressured ultrasound pulses to generate dense cavitating bubble cloud. ...
Influence of three-dimensional reconstruction method for building a model of the cervical spine on its biomechanical responses: A finite element analysis study
(Hindawi Publishing Corporation, 2016)
In some finite element analysis studies of models of sections of the spine, the three-dimensional solid model is built by assuming symmetry about the mid-sagittal plane of the section, whereas in other studies, the model ...
Catalytically competent non-transforming H-RASG12P mutant provides insight into molecular switch function and GAP-independent GTPase activity of RAS
(Nature Publishing Group, 2019)
RAS mutants have been extensively studied as they are associated with development of cancer; however, H-RASG12P mutant has remained untouched since it does not lead to transformation in the cell. To the best of our knowledge, ...
Quantitative phase macroscopic system for label-free imaging of tissue sections
(İstanbul University, 2021)
Optical microscopes are typically designed as versatile tools that are capable of imaging at various modalities with different resolutions in respective visual fields. A large extend of versatility causes increased complexity, ...
S-layer fusion protein as a tool functionalizing emulsomes and CurcuEmulsomes for antibody binding and targeting
(Elsevier, 2015)
Selective targeting of tumor cells by nanoparticle-based drug delivery systems is highly desirable because it maximizes the drug concentration at the desired target while simultaneously protecting the surrounding healthy ...
Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
(Amer Chemical Soc, 2016)
We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ...
Fast and flexible packed string matching
(Elsevier, 2014)
Searching for all occurrences of a pattern in a text is a fundamental problem in computer science with applications in many other fields, like natural language processing, information retrieval and computational biology. ...