Ara
Toplam kayıt 268, listelenen: 221-230
Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage
(Bentham Science Publishers Ltd., 2023)
Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ...
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol
(Georg Thieme Verlag KG, 2023)
Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ...
Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine
(Elsevier B.V., 2023)
Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to extensive first-pass metabolism and is ...
Effects of chitosan nanoparticles with long synthetic siRNAs targeting VEGF in triple-negative breast cancer cells
(Faculdade de Ciencias Farmaceuticas (Biblioteca), 2023)
Vascular endothelial growth factor (VEGF) is an essential angiogenic factor in breast cancer development and metastasis. Small interfering RNAs (siRNAs) can specifically silence genes via the RNA interference pathway, ...
Sesquiterpene coumarin ethers with selective cytotoxic activities from the roots of ferula huber-morathii Peşmen (Apiaceae) and unequivocal determination of the absolute stereochemistry of samarcandin
(MDPI, 2023)
Ancient physicians frequently used the resin of Ferula species to treat cancer. Today, some folkloric recipes used for cancer treatment also contain the resin of Ferula species. The dichloromethane extract of the roots of ...
Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
(Istanbul Medipol University, 2023)
The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were ...
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
(Istanbul University Press, 2023)
Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ...
Phytochemical and in vitro pharmacological evaluation of Phlomis Pungens
(Ankara University, 2022)
Objective: This study aimed to investigate the in vitro wound healing, anti-inflammatory, antimicrobial and antioxidant activity of Phlomis pungens Willd. extract derived from the aerial parts. Material and Method: The ...
Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens
(Marmara University, 2023)
The present study investigated the antibacterial activity of carvacrol against Vancomycin-Resistant Enterococci (VRE), Carbapenem-Resistant Enterobacteriaceae (CRE), Methicillin-Resistant Staphylococcus aureus (MRSA), ...
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
(Marmara University, 2019)
The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ...