Ara
Toplam kayıt 19, listelenen: 11-19
Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites
(Taylor & Francis Ltd, 2016)
Context Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases.Objective In the continuation of our studies on the ...
Two different approaches for oral administration of voriconazole loaded formulations: Electrospun fibers versus beta-cyclodextrin complexes
(MDPI, 2016)
In this work, a comparison between two different preparation methods for the improvement of dissolution rate of an antifungal agent is presented. Poly(epsilon-caprolactone) (PCL) electrospun fibers and beta-cyclodextrin ...
Development and characterization of voriconazole loaded in situ gel formulations for ophthalmic application
(Turkish Pharmacists Assoc, 2016)
The aim of the this research was to prepare and evaluate the potential use of in situ gel formulations for ocular delivery of voriconazole for the treatment of fungal keratitis. An in situ gelling system was used to increase ...
Development and validation of an HPLC method for voriconazole active substance in bulk and its pharmaceutical formulation
(Marmara University, 2016)
The aim of the present study was to develop and validate a High-Performance Liquid Chromatography (HPLC) method for the determination of voriconazole in drug substances and in situ gel. A mixture of acetonitrile and ultrapure ...
Assessment of aprotinin loaded microemulsion formulations for parenteral drug delivery: Preparation, characterization, in vitro release and cytotoxicity studies
(Bentham Science, 2016)
The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ...
Synthesis and antifungal activity evaluation of New 1,2,4-triazole derivatives bearing salicylidene hydrazide moiety
(Bentham Science Publ Ltd, 2016)
A series of new N'-(arylidene)-2-[(1-(4-nitrophenyl)-1H-1,2,4-triazol-3-yl)oxy]acetohydrazide derivatives (116) were prepared and tested for theira ntifungal activity against six plant pathogens, three human pathogens and ...
Synthesis and characterization of novel oxime derivatives
(Bentham Science Publ Ltd, 2016)
Background: The synthesis of effective drugs are very important for the scientist. The various biological effects of the thiazole, oxime and ether functional groups are well known properties by the drug developers. So we ...
Synthesis and antiproliferative activity of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives
(Bentham Science Publ Ltd, 2016)
The synthesis of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives was reported and selected compounds were determined for their anticancer activity evaluation in National Cancer Institute NCI, USA according ...
Effect of microemulsion formulation on biodistribution of Tc-99m-Aprotinin in acute pancreatitis models induced rats
(Taylor & Francis, 2016)
Background: Aprotinin is a monomeric globular polypeptide, which derived from bovine lung tissue and theoretically attractive molecule in ameliorating the effects of acute pancreatitis. Acute pancreatitis is an inflammatory ...