Erişim şekli için "info:eu-repo/semantics/closedAccess" Makale Koleksiyonu listeleme
Toplam kayıt 29, listelenen: 1-20
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The anatomical, morphological features, and biological activity of Scilla siberica subsp. armena (Grossh.) Mordak (Asparagaceae)
(Springer Wien, 2023)Scilla siberica subsp. armena is known as Siberian Squill which is naturally distributed in Lebanon-Syria, Transcaucasus, and Turkey. It is a perennial bulbous plant with a short vegetation period from March to May. In ... -
Anatomical, morphological, and chemical characterizations and biological activities of gagea taurica steven (Liliaceae): A new record for the Turkish Flora
(Wiley, 2023)Gagea genus, which is native to the Mediterranean and Black Sea regions, has attracted significant attention due to its biodiversity and potential health benefits. In this study, the biochemical composition and biological ... -
Antibacterial properties of carvacrol against antibiotic-resistant bacteria, enteric bacteria, and oral pathogens
(Marmara University, 2023)The present study investigated the antibacterial activity of carvacrol against Vancomycin-Resistant Enterococci (VRE), Carbapenem-Resistant Enterobacteriaceae (CRE), Methicillin-Resistant Staphylococcus aureus (MRSA), ... -
Assessment of aprotinin loaded microemulsion formulations for parenteral drug delivery: Preparation, characterization, in vitro release and cytotoxicity studies
(Bentham Science, 2016)The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ... -
The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
(SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Binary synergistic combinations of lavender and fennel essential oils with amoxicillin
(Georg Thieme Verlag, 2023)Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen
(Istanbul Medipol University, 2023)The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and ... -
Chitosan modification-enhanced silencing effect of Ad5-shPDGF-D vector in breast cancer cell line MDA-MB-231
(Bentham Science Publishers, 2023)Background: Gene therapeutics are being developed to treat metastatic breast tumors, which are mostly resistant to conventional therapies. Targeting platelet-derived growth factor-D (PDGF-D) is a viable approach because ... -
Cypsela micro-macromorphological characteristics of selected taxa of Centaurea L. from Turkey and their systematic importance
(Museum National d'Histoire Naturelle, 2023)In this study, the cypsela micro-macromorphological characteristics of 15 Centaurea L. taxa, from the seven sections from Turkey were investigated using Light Microscopy and Scanning Electron Microscopy techniques. The ... -
Cytotoxic, antiproliferative and apoptotic effects of new benzimidazole derivatives on A549 lung carcinoma and C6 glioma cell lines
(Bentham Science Publishers, 2015)Benzimidazole ring is a versatile structure which has been extensively utilized in medicinal chemistry. Since we are working on 1,2-disubstutited benzimidazoles, we have reported new antitumor active derivatives. As a ... -
Dual-drug conjugated glyco-nanoassemblies for tumor-triggered targeting and synergistic cancer therapy
(American Chemical Society, 2022)Drug-conjugated nanoassemblies potentiate the efficiency of anticancer drugs through the advantages of high drug-loading capacity and passive/active targeting ability in cancer therapy. This study describes the synthesis ... -
Evaluation of clinical pharmacist interventions on drugrelated problems in the gastroenterology ward
(Marmara University, 2022)Integrating clinical pharmacists in a multidisciplinary patient care team improves the treatment process by identifying and resolving drug-related problems (DRPs). The aim of the study was to determine the effect of clinical ... -
Evaluation of diet quality and associated factors in geriatric outpatients: A cross-sectional study
(IOS Press, 2023)BACKGROUND: In this study, our aim was to investigate the quality of dietary intake of elderly individuals and to identify the factors that may be associated with their diet quality. METHODS: This cross-sectional study ... -
Evaluation of the antidiabetic property of capparis ovata desf. Var. Palaestina zoh. Extracts using in vivo and in vitro approaches
(Bentham Science Publ Ltd, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Human biomonitoring of trace elements (Zn, Cu, Mn, Cd and As) level in a healthy urban population in Türkiye
(Marmara University, 2023)Human biomonitoring (HBM) studies are carried out to examine the effects of environmental pollutants on human health and to identify risks to public health, with the increasing awareness of environmental pollution around ... -
In vitro ACE2 enzyme inhibitory activity evaluation of different salvia essential oils
(Istanbul Medipol University, 2022)In this present study, commertially available Salvia triloba L., S.officinalis L., and S. sclarea L. essential oils were evaluated for their in vitro angiotensin converting enzyme 2 (ACE2) inhibitory activity. The Salvia ... -
In vitro and in silico evaluation of ACE2 and LOX inhibitory activity of origanum essential oils and carvacrol
(Georg Thieme Verlag KG, 2023)Origanum spp. are used both for culinary purposes and for their biological activities. In this study, commercial Origanum majorana, Origanum minutiflorum, Origanum vulgare, and Origanum onites essential oils and their ... -
In vitro cytotoxicity evaluation and phytochemical analysis of Ajuga reptans L. extracts
(Marmara University, 2023)The aim of this study was to evaluate phytochemical composition of Ajuga reptans L. (Lamiaceae) aerial parts (separately flower and leaf) methanol, aqueous-methanolic extracts, and their cytotoxic activities. The phytochemical ... -
Novel benzimidazole derivatives: Cytotoxic and apoptotic properties on lung cancer cell line
(Bentham Science Publishers, 2020)Background: Benzimidazole derivatives are privileged molecules known to have a wide variety of biological activities. In medicinal chemistry, due to the ring's structural similarity to nucleotides, its derivatives were ... -
Novel benzofurane-pyrazole derivatives with anti-inflammatory, cyclooxygenase inhibitory and cytotoxicity evaluation
(Walter de Gruyter GmbH, 2022)Novel benzofurane-pyrazolone hybrids have been synthesized for evaluating their anti-inflammatory and cytotoxic properties. 4-(2-chloroacetyl)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one were reacted with alpha-hydroxy ...