Bölüm "İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakoloji Ana Bilim Dalı" Makale Koleksiyonu için listeleme
Toplam kayıt 25, listelenen: 1-20
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Antioxidant activity of blackthorn (Prunus spinosa L.) fruit extract and cytotoxic effects on various cancer cell lines
(Logos Medical Publishing, 2019)Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects ... -
Chemical characterization and biological properties of oyster and shiitake mushrooms extracts and their liposomal formulations
(2024)In recent years, the production of liposomal formulations using mushroom extracts has gained increasing interest to increase the bioavailability of bioactive compounds in the nutraceutical field. Based on this information, ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
(Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Combination of exercise and caloric restriction ameliorates nearly complete deleterious effects of aging on cardiovascular hemodynamic and antioxidant system parameters
(Marmara University, 2020)Aging is a progressive and catabolic process by cells of the body are broken down. Study scrutinized the effects of exercise and caloric restriction in cardiovascular hemodynamics and antioxidant system parameters. Rats ... -
Comparison of 3 doses of aloe vera and burn drugs in market on burnt rat models
(İstanbul Medipol University, 2018)Burn injuries are an incident that can have serious traumatic consequences. Degree of tissue damage depends on height of heat and duration of contact. It can be classified as 4 different burn degrees. Herbal treatments can ... -
Effect of glabridin on microvascular permeability of plasma proteins induced by carrageenan
(Biointerface Research in Applied Chemistry, 2022)In present study, investigate the anti-inflammatory effects of glabridin (GLA) in the carrageenan-induced paw edema test of rats. Inflammation is an answer to the body's immune response to various stimuli such as physical ... -
The effects of calorie restriction and exercise on age-related alterations in corpus cavernosum
(Frontiers Media S.A., 2020)Background Aging is an important risk factor for erectile dysfunction (ED). Both calorie restriction (CR) and physical exercise (PE) have been established as a non-medical method for the improvement of detrimental changes ... -
Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol
(Wiley, 2017)Energy drinks (ED) are containing large doses of metabolic stimulants and its use with ethanol has increased dramatically among young adults. In this study, we examined the effects of ED exposure either alone or in combination ... -
Evaluation of antidiabetic activities of scorzonera species on alloxan-induced diabetic mice
(Marmara University Faculty of Health Sciences, 2021)Objective: In Turkish folk medicine, different species of Scorzonera (Asteraceae) have been used in the treatment of various disorders. The study aimed to investigate antidiabetic activity of Scorzonera species and if rutin ... -
Evaluation of the antidiabetic property of capparis ovata desf. Var. Palaestina zoh. Extracts using in vivo and in vitro approaches
(Bentham Science Publ Ltd, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Extract of Glycyrrhiza glabra root attenuates nociception in experimental pain models: The role of BKCa channels
(MS Editions, 2022)The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabra root extract (GGRE) on the large conductance Ca2+-activated K+ (BKCa) channels expressed in the peripheral nervous system by using ... -
Formulation development of liposomal coffee extracts and investigation of their antioxidant capacities
(Elsevier, 2021)he main objective of this study was to carry out the antioxidant capacity of a liposomal formulation either green coffee extract (GCE) and medium roasted coffee extract (RCE) in aq. and MeOH. First, the coffee beans were ... -
Formulation development of Silybum marianum seed extracts and silymarin nanoparticles, and evaluation of hepatoprotective effect
(Editions de Sante, 2023)In this study, we formulated silymarin-nanoparticles and assayed their ability to reduce acetaminophen-induced toxicity in vitro and in vivo. After silymarin molecules were encapsulated the loading efficiency and the ... -
Hypertension-related knowledge, attitudes, and behavior among hypertensive patients in a community pharmacy in Sivas, Türkiye: A regional descriptive study
(Istanbul Medipol University, 2023)This study scrutinized hypertension-related knowledge, attitudes, and behavior among patients with hypertension. It was performed with 88 hypertensive patients in a community pharmacy in Sivas for one month. Suitably ... -
The importance of computerized drug interaction checker programs used in community pharmacies to avoid potential drug interactions: A preliminary study with clarithromycin
(Istanbul Training & Research Hospital, 2019)Introduction: Drug-drug interactions (DDI) due to multiple drug use are the most important cause of adverse drug reactions. DDIs are among medication errors that can be prevented. The integrated computerized drug interaction ... -
Miyokardiyal iskemi sonrası gelişen akut böbrek hasarı üzerine Nebivolol’ün etkisi: Preklinik bir çalışma
(Galenos Yayıncılık, 2018)Amaç: Akut miyokard iskemisinin reperfüzyonu (IR) sırasında miyokard dokusunun yanı sıra diğer dokularda da hasarın söz konusu olduğu gösterilmiştir. Böbrek hasarı bunlardan birisidir. Altta yatan mekanizmalara yönelik pek ... -
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
(Istanbul University Press, 2023)Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ... -
Nitric oxide mediated effects of nebivolol on erectile function in rats with heart failure
(IMR Press, 2022)Background and objective: Heart failure (HT) is a common complication of cardiovascular disease, which leads to functional cardiac abnormalities. Beta-blockers are commonly used to reduce mortality in HF patients; however, ... -
Obturator neuropathy combined with Guillain-Barre syndrome
(Istanbul Medipol University, 2020)Obturator neuropathy caused by entrapment of obturator nerve is a disease with numbness, pain and weakness in legs. Guillain-Barre syndrome is an immune-me-diated peripheral polyneuropathy characterized by nearly same ... -
Panax ginseng extract ameliorates methotrexate-induced multi-organ damage via the regulation of oxidative stress
(Marmara University, 2023)Oxidative damage plays an important role in organ toxicities caused by methotrexate (MTX). This study aimed to determine the antioxidant effects of Panax ginseng (PxG) extract against MTX-induced liver, lung, ileum and ...