Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 274, listelenen: 200-219
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Phytochemical profile and antioxidant activity potential of Lotus sanguineus (Vural) D.D.Sokoloff
(Istanbul Medipol University, 2024)The in vitro antioxidant activity and phenol, phenolic acid, flavonoid, and proanthocyanidin content of Lotus sanguineus (Vural) D.D.Sokolof extracts were investigated. The aerial parts of Lotus sanguineus have high ... -
Phytochemical screening, biological evaluation, anatomical, and morphological investigation of Ferula tingitana L. (Apiaceae)
(Springer Wien, 2023)Ferula tingitana L. is a high perennial plant and its leaf is an alternate arrangement and yellow, and its flowers are unisexual like other Apiaceae. It has been used as a spice and for various medicinal purposes in the ... -
Platinum(II)-thiosemicarbazone drugs override the cell resistance due to glutathione; assessment of their activity against human adenocarcinoma cells
(Taylor & Francis Ltd, 2016)New platinum(II) compounds of the thiosemicarbazone 1-(1H-Benzimidazol-2-yl)ethan-1-one thiosemicarbazone (BzimetTSCH), [Pt(BzimetTSCH)Cl]center dot 2H(2)O (1) and [Pt(BzimetTSCH)(tpp)]Cl center dot H2O center dot MeCN (2) ... -
Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin
(Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest ... -
Potent ribonucleotide reductase inhibitors: Thiazole-containing thiosemicarbazone derivatives
(Wiley, 2019)The antioxidant, antimalarial, antibacterial, and antitumor activities of thiosemicarbazones have made this class of compounds important for medicinal chemists. In addition, thiosemicarbazones are among the most potent and ... -
Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine
(Taylor & Francis Ltd, 2017)The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of benzocaine (BZN). The pseudoternary-phase diagrams were constructed ... -
Preparation, optimization and in vivo anti-inflammatory evaluation of hydroquinone loaded microemulsion formulations for melasma treatment
(Marmara University, 2019)The aim of the study is to evaluate the strengthening of penetration of the epidermis through the formulas containing hydroquinone in melasma treatment and development of alternative new carrier systems. During preparation ... -
The prevalence of drug-drug interactions and reported therapy related side-effects in oncology out-patients
(Marmara University, 2023)Objective: The use of multiple medications in cancer patients is unavoidable; thus, adverse drug-drug interactions are frequent. This study aims to assess the prevalence of potential drug interactions in oncology patients ... -
Prognostic significance of tumor tissue NeuGcGM3 ganglioside expression in patients receiving racotumomab immunotherapy
(Hindawi Ltd., 2020)Expression ofN-glycolyl GM3 (NeuGcGM3) ganglioside was detected in the tumor specimens of patients who were on Racotumomab anti-idiotype vaccine maintenance treatment, and prognostic significance as a biomarker was ... -
A prospective study concerning the effect of pharmaceutical care services on patients with heart failure
(Marmara University, 2022)Objective: Heart failure (HF), caused by an abnormality in cardiac function, is the inability of heart tissue to pump blood or deliver sufficient oxygen, resulting in abnormal diastolic volume. Drug-Related Problems (DRPs) ... -
Protective effect of N-Acetyl-L-Cysteine (NAC) on endosulfan-induced liver and kidney toxicity in rats
(E-Century Publishing Corp, 2017)Endosulfan-induced systemic toxicity arises from oxidative stress and glutathione depletion. This study aims to investigate the possible protective effect of N-acetyl-L-cysteine (NAC) against endosulfan-induced toxicity ... -
Protective effects of momordica charantia (Bitter Melon) against metho-trexate-induced kidney damage
(Bentham Science Publishers, 2023)Background: Methotrexate is a cytotoxic chemotherapeutic agent that has severe side ef-fects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Protective effects of momordica charantia (Bitter Melon) against methotrexate-induced kidney damage
(Bentham Science Publishers Ltd., 2023)Background Methotrexate is a cytotoxic chemotherapeutic agent that has severe side effects, such as nephrotoxicity. Momordica charantia is a bright yellow-orange fruity plant that has been shown to have antioxidant, ... -
Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri
(2017)Farelerde oluşturduğumuz deneysel yara modellerinde, Prunus Spinosa L. metanollü meyve ekstresini kullanarak, bu ekstrenin yara iyileşmesindeki etkisini araştırdık. Otuz iki adet C57/Black fare ile 4 deney grubu oluşturuldu. ... -
Pyridine-substituted thiazolylphenol derivatives: Synthesis, modeling studies, aromatase inhibition, and antiproliferative activity evaluation
(Wiley-VCH Verlag, 2018)Drugs used in breast cancer treatments target the suppression of estrogen biosynthesis. During this suppression, the main goal is to inhibit the aromatase enzyme that is responsible for the cyclization and structuring of ... -
Quality by design approach for optimizing preparation and characterization of buccal film formulation with different polymers
(Advanced Scientific Research, 2019)Bilayered oromucosal film preparations (buccal films) offer a promising way to enable drug administration via the oral cavity. Polymeric film formulations containing chitosan, sodium alginate or carbopol were evaluated to ... -
A quantum chemical DFT/HF study on acidity constants of some benzothiazole and thiazole derivatives
(Council of Scientific and Industrial Research, 2014)The acid dissociation (K-a) constants of some 4-and/or 6-substituted-2-aminobenzothiazole compounds have been investigated theoretically. The gas and aqueous phase geometries, thermal and solvation free energies have been ... -
Rational design of cathode structure based on free-standing S/rGO/CNT nanocomposite for Li-S batteries
(Elsevier Science, 2020)Sulfur / reduced graphene oxide / carbon nanotube (S/rGO/CNT) composite cathodes were fabricated as laminar-structured free-standing papers to develop high-capacity lithium sulfur batteries (Li-S). Here, the rGO content ... -
Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish
(Taylor & Francis Ltd, 2022)Among the mechanisms underlying Parkinson’s disease, many pathogenic mechanisms are suggested to be effective such as oxidative stress, mitochondrial dysfunction, disruption of the ubiquitin-proteasome system, and ... -
The role of pharmacists in Kırklareli (Turkey) as primary health care providers
(University of Istanbul, 2017)This study was carried out in Kırklareli in 2005. The aim was to investigate the role of pharmacists as primary health care providers. In 63.5% of the total number of 55 pharmacies taking part in the research, there was ...
