Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 280, listelenen: 201-220
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Synthesis and antibacterial evaluation of novel benzimidazole, benzothiazole, benzofurane, and naphtofurane derivatives of aminothiazoles
(Ankara Association of Pharmaceutical Sciences, 2022)The thiazole ring is the core of bioactive molecules that generate broad activity. These activities include anticonvulsant, antimicrobial, antituberculosis, antiviral, etc. In this work, starting from seconder/cyclic amines, ... -
Evaluation of drug-drug interactions and side effects in COVID-19 patients in an intensive care unit
(Galenos Publishing House, 2022)BACKGROUND/AIM: Considering comorbidity rates in patients diagnosed with coronavirus disease 2019 (COVID-19), polypharmacy will be inevitable when the treatment for COVID-19 is added to the treatment of existing chronic ... -
Increasing the biocompatibility of graphene-based hybrid nanostructures with glycopolymer
(Scientific Technical Research Council Turkey-TUBITAK, 2022)Hybrid nanostructures decorated with glycopolymers are appropriate for biomedical applications. In this paper, the results are obtained from nanographene (NG) decorated with glycoblock copolymer to increase their potential ... -
Phytochemical and in vitro pharmacological evaluation of Phlomis Pungens
(Ankara University, 2022)Objective: This study aimed to investigate the in vitro wound healing, anti-inflammatory, antimicrobial and antioxidant activity of Phlomis pungens Willd. extract derived from the aerial parts. Material and Method: The ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Investigation of hidden crisis of prescription drug abuse in Turkey: Pregabalin monitoring
(Istanbul Medipol University, 2022)This is a cross-sectional retrospective observational national study. Abuse/misuse of the pregabalin and related parameters analyzed. Pregabalin was mostly pre-scribed by general practitioners (26.2%). Pregabalin prescribing ... -
Discovery of novel potent human chondrosarcoma (SW1353) inhibitors: 4-(2/3/4-pyridyl)thiazole 2-acetamide derivatives
(Elsevier B.V., 2023)Chondrosarcoma is the most common cartilage sarcoma among adult patients. It is mainly observed after the degradation of chondrocytes in the case of cell stress. Unfortunately, the mortality among patients is high as a ... -
Phytochemical analysis, antioxidant, and enzyme inhibition activity of five Salvia taxa from Turkey
(Elsevier B.V., 2023)Salvia L. species are widely used for treatment of different disorders in traditional Turkish medicine. In this study, the methanol extracts of five Salvia taxa, including S. aucheri subsp. canescens, S. aytachii, S. ... -
In Vitro Antiviral Evaluations of Coldmix®: An Essential Oil Blend against SARS-CoV-2
(NLM (Medline), 2023)Coldmix® is a commercially available Eucalyptus aetheroleum and, Abies aetheroleum blend for medicinal applications. In this present study, the in vitro antiviral potential of Coldmix®, and its major constituents 1,8-cineole ... -
Novel hybridized computational paradigms integrated with five stand-alone algorithms for clinical prediction of HCV status among patients: A data-driven technique
(MDPI, 2023)The emergence of health informatics opens new opportunities and doors for different disease diagnoses. The current work proposed the implementation of five different stand-alone techniques coupled with four different novel ... -
Cypsela micro-macromorphological characteristics of selected taxa of Centaurea L. from Turkey and their systematic importance
(Museum National d'Histoire Naturelle, 2023)In this study, the cypsela micro-macromorphological characteristics of 15 Centaurea L. taxa, from the seven sections from Turkey were investigated using Light Microscopy and Scanning Electron Microscopy techniques. The ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen
(Istanbul Medipol University, 2023)The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and ... -
Biological activities of the fruit essential oil, fruit, and root extracts of ferula drudeana korovin, the putative anatolian ecotype of the silphion plant
(MDPI, 2023)In the present study, preliminary phytochemical investigations were performed on the fruit essential oil and antioxidant-rich methanolic extracts of the fruits and roots of Ferula drudeana, the putative Anatolian ecotype ... -
Surgical orthopedic patients’ perception of antibiotic use and antibiotic resistance
(University of Ankara, 2023)Objective: The aim of the study was to evaluate orthopedic patients' knowledge of antibiotics and antibiotic resistance. Material and Method: Patients admitted to the hospital for orthopedic surgery were given a questionnaire ... -
Formulation development of Silybum marianum seed extracts and silymarin nanoparticles, and evaluation of hepatoprotective effect
(Editions de Sante, 2023)In this study, we formulated silymarin-nanoparticles and assayed their ability to reduce acetaminophen-induced toxicity in vitro and in vivo. After silymarin molecules were encapsulated the loading efficiency and the ... -
Bioautography for evaluation of several Lavandula L. and origanum species antimicrobial and antioxidant activity
(Istanbul Medipol University, 2023)In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal ... -
Hypertension-related knowledge, attitudes, and behavior among hypertensive patients in a community pharmacy in Sivas, Türkiye: A regional descriptive study
(Istanbul Medipol University, 2023)This study scrutinized hypertension-related knowledge, attitudes, and behavior among patients with hypertension. It was performed with 88 hypertensive patients in a community pharmacy in Sivas for one month. Suitably ... -
Evaluation of venous thromboembolism prophylaxis in cancer patients: A retrospective study
(Istanbul Medipol University, 2023)This study aims to evaluate the prophylaxis of venous thromboembolism (VTE) in cancer patients. This retrospective study included 100 adult patients of different ages and genders who applied to the University Hospital ... -
Synthesis and antiproliferative evaluation of new 1,3,5-trisubstituted 1,2,4-triazole derivatives against glioblastoma cell lines
(Wiley, 2023)A series of novel 1,3,5-trisubstituted-1,2,4-triazole derivatives were successfully synthesized from the starting materials of caffeic acid (CA) and ferulic acid (FA) in moderate to good yields (45-71 %). All novel compounds ... -
Development, characterization of naringenin-loaded promising microemulsion formulations, and demonstration of anti-aging efficacy by in vitro enzyme activity and gene expression
(Editions de Sante, 2023)This study aims to produce microemulsion formulations containing naringenin for anti-aging reasons. For this purpose, formulations of topical microemulsions including different cosurfactants and surfactants were developed, ...