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Toplam kayıt 280, listelenen: 181-200
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The effect of chamomile extract on blood sugar level, lipid profile and body weight in high-fat diet fed rats
(Istanbul Medipol University, 2022)The addition of herbs to the diet is one of the methods for the treatment of obesity. It is aimed to examine the extracts of chamomile to use in the treatment of obesity, against high-fat diet. In this study, 6-8 weeks old ... -
In vitro ACE2 and 5-LOX inhibition of rosmarinus officinalis l. essential oil and its major component 1,8-cineole
(ACG Publications, 2022)In this present study, Rosmarinus officinalis L. essential oil, and its major component 1,8-cineole was evaluated in vitro for angiotensin converting enzyme 2 (ACE2), as well as for 5-lipoxygenase (5-LOX) enzyme inhibitory ... -
Evaluation of clinical pharmacist interventions on drug-related problems in the gastroenterology ward
(Marmara University, 2022)Integrating clinical pharmacists in a multidisciplinary patient care team improves the treatment process by identifying and resolving drug-related problems (DRPs). The aim of the study was to determine the effect of clinical ... -
Cytotoxic activity of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin
(Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichlorometh-ane extract of the fruits of H. anatolica showed the ... -
In vitro ACE2 enzyme inhibitory activity evaluation of different salvia essential oils
(Istanbul Medipol University, 2022)In this present study, commertially available Salvia triloba L., S.officinalis L., and S. sclarea L. essential oils were evaluated for their in vitro angiotensin converting enzyme 2 (ACE2) inhibitory activity. The Salvia ... -
ACE2 and LOX enzyme inhibitions of different lavender essential oils and major components linalool and camphor
(American Chemical Society, 2022)In this present study, Lavandula angustifolia, Lavandula stoechas, and Lavandula x heterophylla essential oils and their main compounds linalool and camphor were evaluated in vitro for lipoxygenase enzyme (LOX) and for ... -
Nafion/aquivion-based composite lithium ion exchange membranes for high capacity Li-S batteries
(Wiley-VCH Verlag GmbH, 2022)Lithiated Nafion (Li-Naf) and lithiated Aquivion (Li-Aqu) ion exchange membranes are applied as electrolyte and separator to prevent the polysulfide shuttle effect in Li−S batteries. The production and characterization of ... -
Biological properties and HPLC analyses of four medicinal plants extracts obtained at different extraction temperatures
(Wiley, 2022)In the present study, extracts of four medicinal plants (Cajanus cajan, Carica papaya, Morinda morindoides, and Senna alexandrina) obtained at two different extraction temperatures (24 and 45 degrees C) were investigated ... -
Synthesis and in vitro antitumor activities of novel thioamide substituted piperazinyl-1,2,4-triazines
(Wiley, 2022)Triazines are in great interest for their potential to mimic nucleoside analog compounds. Three different isomers exist including 1,2,3-triazine, 1,3,5-triazine (s-triazine) and 1,2,4-triazine. All of these skeletons were ... -
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
(Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin
(Istanbul Medipol University, 2022)Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest ... -
Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds
(Walter de Gruyter GmbH, 2022)In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were ... -
Evaluation of educational needs of diabetic patients
(Faculty of Pharmacy of Ankara University, 2022)Objective: Our study aimed to assess the role of pre-graduate pharmacy students’ participation in a diabetic education program on improving diabetic self-care. Material and Method: This study included both a cross-sectional ... -
Screening of antimicrobial, antioxidant, antidiabetic activities, anatomical and morphological properties of Colchicum speciosum Steven (Colchicaceae)
(Springer, 2022)Colchicum speciosum Steven species is a perennial stemless plant. C. speciosum is a flowering herb native to mountainous regions of northern Turkey, the Caucasus, and northern Iran. It has been known as "Vargit, Aci cigdem, ... -
Epidemiology of nosocomial candidemia, mortality, and antifungal resistance: 7-year experience in Turkey
(National Institute of Health, 2022)Candidemia is an important clinical condition that prolongs hospital stays and increases morbidity, mortality, and hospital costs. The aim of this retrospective study was to evaluate the epidemiological and microbiological ... -
Dual-drug conjugated glyco-nanoassemblies for tumor-triggered targeting and synergistic cancer therapy
(American Chemical Society, 2022)Drug-conjugated nanoassemblies potentiate the efficiency of anticancer drugs through the advantages of high drug-loading capacity and passive/active targeting ability in cancer therapy. This study describes the synthesis ... -
Nitric oxide mediated effects of nebivolol on erectile function in rats with heart failure
(IMR Press, 2022)Background and objective: Heart failure (HT) is a common complication of cardiovascular disease, which leads to functional cardiac abnormalities. Beta-blockers are commonly used to reduce mortality in HF patients; however, ... -
Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
(Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Antioxidant activity and anti-cancer effects of bilberry (vaccinium myrtillus l.) fruit extract on gastric cancer, ags cell line
(Ankara University, 2022)Objective: Vaccinium myrtillus L. fruits are consumed as food. This research was aimed to evaluate V. myrtillus methanol extract antioxidant and cytotoxic activities and determine its anti-cancer potential to further study ... -
A prospective study concerning the effect of pharmaceutical care services on patients with heart failure
(Marmara University, 2022)Objective: Heart failure (HF), caused by an abnormality in cardiac function, is the inability of heart tissue to pump blood or deliver sufficient oxygen, resulting in abnormal diastolic volume. Drug-Related Problems (DRPs) ...
