Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 354, listelenen: 61-80
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Evidence that melatonin downregulates Nedd4-1 E3 ligase and its role in cellular survival
(Academic Press Inc Elsevier Science, 2019)Indolamine melatonin structurally resembles non-covalent proteasome inhibitors; however, the role of ubiquitin proteasome system (UPS) in neuronal survival and how melatonin carries out UPS inhibition remain largely unknown. ... -
Comparison of immediate vs deferred cytoreductive nephrectomy in patients with synchronous metastatic renal cell carcinoma receiving sunitinib: The surtime randomized clinical trial
(American Medical Association, 2019)IMPORTANCE In clinical practice, patients with primary metastatic renal cell carcinoma (mRCC) have been offered cytoreductive nephrectomy (CN) followed by targeted therapy, but the optimal sequence of surgery and systemic ... -
Internet addiction, fatigue, and sleep problems among adolescent students: A large-scale study
(Springer New York LLC, 2019)The aim of the present study was to examine the association between Internet addiction (IA), fatigue, and sleep problems among university students. A total of 3000 Turkish students aged 18 to 25 years were approached and ... -
Systematic review and cumulative analysis of the managements for proximal impacted ureteral stones
(Springer Verlag, 2019)Purpose: To compare the efficacy and safety of different treatment options for the management of proximal impacted ureteral stones (PIUS). Methods: A systematic literature search using Pubmed, Medline, Embase and Cochrane ... -
Vitamin d and elevated serum uric acid as novel predictors and prognostic markers for type 2 diabetes mellitus
(Wolters Kluwer Medknow Publications, 2019)Aim: To ascertain the active role of uric acid and vitamin D as potential biomarkers for impaired glucose metabolism among people living with type 2 diabetes mellitus (T2DM) in Turkish community. Subjects and Methods: This ... -
Compliance of medical biochemistry education in medical schools with national core education program 2014
(Walter De Gruyter Gmbh, 2019)Background: Medical school curriculums are not standardized in Turkey and around the world, which results in great diversity in education. National Core Education Program (NCEP) has been prepared as a frame program and the ... -
Comparison of serum biochemical markers in patients with mesothelioma and pleural plaques versus healthy individuals exposed to environmental asbestos
(Baycinar Medical Publishing, 2019)Background: In this study, we aimed to compare serum biochemical markers in patients with malignant pleural mesothelioma and pleural plaques versus healthy individuals exposed to environmental asbestos. Methods: Between ... -
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
(Czech Medical Soc, 2019)Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ... -
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
(Academic Press Inc Elsevier Science, 2019)Warburg hypothesized that the energy consumption of cancer cells is different than the normal cells. When compared to normal conditions, cancer cells do not undergo tricarboxylic acid (TCA) cycle therefore resulting in ... -
Novel synthetic approaches for bisnaphthalimidopropyl (BNIP) derivatives as potential anti-parasitic agents for the treatment of leishmaniasis
(MDPI, 2019)Leishmaniasis is a neglected parasitic disease that is widely seen in more than 60 countries worldwide, including Turkey and its subcontinental region. There are several chemotherapy agents for the treatment of leishmaniasis, ... -
Assessment of the Gail model in estimating the risk of breast cancer: Effect of cancer worry and risk in healthy women
(Asian Pacific Organization for Cancer Prevention, 2019)Background: There has been substantial interest in developing methods to predict the risk of breast cancer. The Gail model is one the first model have been widely used to identify women at higher risk of breast cancer. ... -
Bedside ultrasonography for the confirmation of gastric tube placement in the neonate
(Wolters Kluwer Medknow Publications, 2019)Background: Naso/Orogastric tube (NOGT) misplacement can lead to significant complications. Therefore, the assessment of tube position is essential to ensure patient safety. Although radiography is considered the gold ... -
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ... -
Recommended antibiotic prophylaxis regimen in retrograde intrarenal surgery: Evidence from a randomised controlled trial
(Blackwell Publishing Ltd, 2019)Objective: To study the incidence of postoperative systemic inflammatory response syndrome (SIRS) following different antibiotic prophylaxis (ABP) regimens in retrograde intrarenal surgery (RIRS). Patients and Methods: ... -
Electrophysiological evidence of altered facial expressions recognition in Alzheimer's disease: A comprehensive ERP study
(Elsevier Ireland Ltd, 2019)Objectives: The present study aims to evaluate the amplitude and latency of event-related potentials (ERPs) P100, N170, VPP and N230 in individuals with Alzheimer's disease (AD) compared to healthy elderly controls, using ... -
Focal laser ablation as clinical treatment of prostate cancer: Report from a Delphi consensus project
(Springer Verlag, 2019)Purpose: To define the role of focal laser ablation (FLA) as clinical treatment of prostate cancer (PCa) using the Delphi consensus method. Methods: A panel of international experts in the field of focal therapy (FT) in ... -
Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences
(Sage Publications LTD, 2019)Background: At present, it is not possible to predict the ablation zone volume following irreversible electroporation (IRE) for prostate cancer (PCa). This study aimed to determine the necessary electrical field threshold ... -
Confocal laser endomicroscopy for upper tract urothelial carcinoma: Validation of the proposed criteria and proposal of a scoring system for real-time tumor grading
(Springer Verlag, 2019)Purpose: Confocal laser endomicroscopy (CLE) is a fluorescence-based fiber-optic imaging technique with the potential for intraoperative grading of upper tract urothelial carcinoma (UTUC). This study aims to (1) investigate ... -
Integrative analysis of axolotl gene expression data from regenerative and wound healing limb tissues
(Nature Research, 2019)Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ... -
Is there a relationship between microvascular complications and the severity of type 2 diabetes mellitus?
(Erciyes University Faculty Of Medicine, 2020)Objective: The aim of this study was to determine the relationship between microvascular Type 2 diabetes mellitus (T2DM) complications and the severity and duration of diabetes in the light of sociodemographic and lifestyle ...