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Metaproteogenomic analysis of saliva samples from Parkinson's disease patients with cognitive impairment
(Nature Portfolio, 2023)Cognitive impairment (CI) is very common in patients with Parkinson's Disease (PD) and progressively develops on a spectrum from mild cognitive impairment (PD-MCI) to full dementia (PDD). Identification of PD patients at ... -
Technical aspects and clinical limitations of sperm DNA fragmentation testing in male infertility: A global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) is a functional sperm abnormality that can impact reproductive potential, for which four assays have been described in the recently published sixth edition of the WHO laboratory manual ... -
Active shrinkage protects neurons following axonal transection
(Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
When bladder and brain collide: Is there a gender difference in the relationship between urinary incontinence, chronic depression, and anxiety?
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)In longitudinal and cross-sectional studies, depression and anxiety have been associated with urinary incontinence (UI) in women. However, this association has not been studied in men. Utilizing data from the 2008 Turkish ... -
The impact of chiral switch on drug labeling in Turkey: Indication, posology, and adverse effects
(Marmara University, 2023)Objective: Chiral switch, which involves replacing racemic drugs to market them as pure enantiomers, is presumed to improve efficacy and safety. Data on how chiral switch-related changes are represented in summary of product ... -
A longitudinal study of the association between depression, anxiety and stress symptoms of university students in Serbia with excessive social media use before and during COVID-19 pandemic
(Frontiers Media SA, 2023)Background: Besides the well known good side of social media, it cannot be denied some of its negative effects. This two-phase study aimed to find out whether the usage of social media during the COVID-19 pandemic showed ... -
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
(Springer, 2023)Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young ... -
Examining the tapestry of mental health crises in low-& middle-income countries: An intercontinental analysis of the contributing factors and instructive approaches
(University of Faisalabad, 2023)In recent decades, the intricate landscape of mental health challenges has become a focal point of global concern, with particular urgency in Low-and Middle-Income Countries (LMICs). This manuscript delves into the ... -
Triggers and regulation: The gut microbiome in rheumatoid arthritis
(Taylor and Francis Ltd., 2023)Introduction Rheumatoid arthritis is a chronic inflammatory disease marked by systemic symptoms and joint degeneration. Interestingly, the development and progression of rheumatoid arthritis have been linked to the microbiome, ... -
The impact of single-use digital flexible cystoscope for double J removal on hospital costs and work organization: A multicentric evaluation
(SAGE Publications Ltd, 2023)Background: Isiris-alpha (R) is a single-use digital flexible cystoscope with an integrated grasper designed for double J (DJ) stent removal. Aim of this study was to conduct a multicentric evaluation of the costs and ... -
The impact of type D personality traits on quality of life, sleep, anxiety, and depression in fibromyalgia patients: A comparative study with healthy controls
(International Scientific Information, Inc., 2023)Background: Type D personality has been associated with adverse clinical outcomes and poor quality of life in many diseases. This study aimed to evaluate the effects of type D personality on pain, anxiety and depression, ... -
Evaluation of infant mortality before and during covid-19 pandemic in a district of İstanbul
(Turkish Society of Public Health Specialists, 2023)Objective: The aim of this study is to evaluate infant mortality in 2019 and 2020 years at the local level, considering the beginning of the pandemic period. Methods: The population of this cross-sectional study are infants ... -
Weight loss and beyond, assessment of quality of life after laparoscopic sleeve gastrectomy using baros in patients with obesity in Turkey
(Acta Endocrinologica Foundation, 2023)Context. Sleeve gastrectomy is an effective method for management of obesity. The Bariatric Analysis and Reporting Outcome System (BAROS) is a comprehensive and standard system for the assessment of outcomes of weight loss ... -
Multiple mask and boundary scoring R-CNN with cGAN data augmentation for bladder tumor segmentation in WLC videos
(Elsevier B.V., 2024)Automatic diagnosis systems capable of handling multiple pathologies are essential in clinical practice. This study focuses on enhancing precise lesion localization, classification and delineation in transurethral resection ... -
Association of arbitrary prescribing behavior to costly drug expenditures: A pharmacoeconomic study in primary care
(Oxford University Press, 2024)Background: We aimed to examine the cost-related prescribing performance of primary care physicians who had a higher versus lower tendency of arbitrary prescribing. Methods: In this cross-sectional study, we evaluated the ... -
Evaluation of pathologically confirmed benign inflammatory breast diseases using artificial intelligence on ultrasound images
(Spanish Society of Senology and Breast Pathology, 2024)Objectives: It was aimed to use AI retrospectively to evaluate US images of pathologically confirmed benign inflammatory lesions, to compare the results of AI with our US reports, and to test the reliability of AI in itself. ... -
Inflammatory and Hematologic Liver and Platelet (HALP) Scores in Hypothermia-Treated Hypoxic–Ischemic Encephalopathy (HIE)
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Objective: This study examined systemic inflammatory indices and “Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) scores” in neonates with hypoxic–ischemic encephalopathy (HIE). Methods: A total of 43 neonates with ... -
Family physicians overestimate diagnosis probabilities regardless of the test results
(Frontiers Media SA, 2024)Introduction: As useful tools for clinical decision-making, diagnostic tests require careful interpretation in order to prevent underdiagnosis, overdiagnosis or misdiagnosis. The aim of this study was to explore primary ... -
Functional neural networks stratify Parkinson's disease patients across the spectrum of cognitive impairment
(Wiley, 2024)Introduction Cognitive impairment (CI) is a significant non-motor symptoms in Parkinson's disease (PD) that often precedes the emergence of motor symptoms by several years. Patients with PD hypothetically progress from ... -
The impact of cigarette smoking, water-pipe use on hearing loss/hearing impairment: A cross-sectional study
(Asian Pacific Organization for Cancer Prevention, 2024)OBJECTIVE: The aim of the present study was to determine the association between cigarette smoking, waterpipe smoking, and co-morbidity diseases on hearing loss. METHODS: A cross-sectional study was conducted among 1015 ...