Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 355, listelenen: 241-260
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Stimuli-responsive theranostic system: A promising approach for augmented multimodal imaging and efficient drug release
(Elsevier B.V., 2022)Destruction of drug resistant and invisible micro-tumors requires innovative screening and treatment modalities. Theranostic nanosystems offering multimodal imaging and therapy are attractive platforms with potential to ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
(Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
Lamotrigine derivatives-synthesis, anti-cancer, and anti-MDR-bacterial activities
(Elsevier B.V., 2022)A new series of quaternary ammonium salts 3–21 of lamotrigine (6-(2, 3-dichlorophenyl)-1, 2, 4-triazine-3, 5-diamine) was synthesized via N-alkylation of lamotrigine using different benzyl bromides. The new analogues were ... -
Human macrophages directly modulate iPSC-derived cardiomyocytes at healthy state and congenital arrhythmia model in vitro
(Springer Heidelberg, 2022)The electrophysiological regulation of cardiomyocytes (CMs) by the cardiac macrophages (M Phi s) has been recently described as an unconventional role of M Phi s in the murine heart. Investigating the molecular and ... -
Antileishmanial activity of BNIPdaoct- and BNIPdanon-loaded emulsomes on leishmania infantum parasites
(Frontiers Media S.A., 2022)Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ... -
Preoperative screening for COVID-19: Results from a clinical diagnostic laboratory
(Istanbul University, 2022)Objective: The study aimed to determine what proportion of Turkiye’s preoperative patient population has tested positive for COVID-19 and to ascertain whether the increasing or decreasing trend in the numbers of positive ... -
The association of chiral characteristic with drug withdrawal due to safety: A comparative analysis
(Wiley, 2023)Aims Chirality of drugs might be associated with safety issues through pharmacokinetic or pharmacodynamic variations, interactions, or direct toxicological responses. We aimed to compare chiral status of the available drugs ... -
Evaluation of nutritional status with Healthy Eating Index (HEI-2010) of syrian refugees living outside the refugee camps
(MDPI, 2023)Nutrition is a public health issue. Amongst populations of refugees, unmet nutritional needs have been identified. The aim of this study was to evaluate the nutritional status of Syrian refugees living outside the refugee ... -
EMAS position statement: Vitamin D and menopausal health
(Elsevier Ireland Ltd, 2023)Introduction: There is increasing evidence that vitamin D has widespread tissue effects. In addition to osteoporosis, vitamin D deficiency has been associated with cardiovascular disease, diabetes, cancer, infections and ... -
Epidemiological trends and clinical features of the ongoing monkeypox epidemic: A preliminary pooled data analysis and literature review
(Wiley, 2023)An emerging outbreak of monkeypox infection is quickly spreading worldwide, being currently reported in more than 30 countries, with slightly less than 1000 cases. In the present preliminary report, we collected and ... -
Celebrities and medical awareness—The case of celine dion and stiff-person syndrome
(MDPI, 2023)The positive role of celebrities in spreading important medical information and contributing to increasing public awareness regarding the diagnosis, treatment, and prevention of various medical conditions cannot be ... -
Impact of previous malignancy at diagnosis on oncological outcomes of upper tract urothelial carcinoma
(NLM (Medline), 2023)BACKGROUND: The evidence of prognostic factors and individualized surveillance strategies for upper tract urothelial carcinoma are still weak. OBJECTIVES: To evaluate whether the history of previous malignancy (HPM) affects ... -
Herpes simplex virus and SLE: Though uncommon yet with significant implications
(NLM (Medline), 2023)To the Editor,The relation between infectious agents, particularly viruses, withautoimmunity and autoimmune diseases, has been extensivelystudied during the last decades. Recently, the association was shownto be even ... -
Effect of focal vs extended irreversible electroporation for the ablation of localized low- or intermediate-risk prostate cancer on early oncological control: A randomized clinical trial
(American Medical Association, 2023)Importance: Focal ablative irreversible electroporation (IRE) is a therapy that treats only the area of the tumor with the aim of achieving oncological control while reducing treatment-related functional detriment. Objective: ... -
Association of diabetes, hypertension, and their combination with basal symptoms and treatment responses in overactive bladder patients
(Frontiers Media S.A., 2023)Introduction: Pelvic hypoperfusion caused by atherosclerosis has been proposed as a cause of lower urinary tract dysfunction including overactive bladder syndrome (OAB). Limited data indicate that OAB patients with concomitant ... -
Comparison of primary care prescriptions for old and very old hypertensive patients
(TÜBİTAK (Scientific and Technological Research Council of Türkiye), 2023)Background/aim: Elderly and very elderly individuals might be subject to different approaches for the treatment of hypertension. We aimed to compare drug utilization in hypertensive old patients and very old patients in ... -
Alterations in biochemical profiles of patients with severe COVID-19 pneumonia: Analysis of repeated laboratory tests
(Kare Publishing, 2023)Objective: This study was initiated to show the changes in the biochemical profile and identify the mortality risk factors of patients with severe coronavirus disease-19 (COVID-19) pneumonia. Materials and Methods: This ... -
Anaphylactoid reactions following red blood cell transfusion in a patient with previously undiagnosed immunoglobulin a deficiency: Case report
(AVES, 2023)A 73-year-old, 104 kg female patient was hospitalised for debulking and low anterior colon resection operations. Anaphylactoid symptoms devel-oped when administering erythrocyte suspension and fresh frozen plasma. Through ... -
Comparison of medical treatment and acupuncture in treatment of psychogenic erectile dysfunction: a prospective, randomized, placebo-controlled study
(Düzce University, 2023)Objective: Erectile dysfunction (ED) is the persistent inability to achieve or maintain an erection that is sufficient for satisfactory sexual performance. The aim of this study was to assess the impact of acupuncture in ...