Yayın tarihi için Makale Koleksiyonu listeleme
Toplam kayıt 354, listelenen: 201-220
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Mechanistic insight into impact of phosphorylation on the enzymatic steps of farnesyltransferase
(Wiley, 2022)Farnesyltransferase (FTase) is a heterodimeric enzyme, which catalyzes covalent attachment of the farnesyl group to target proteins, thus coordinating their trafficking in the cell. FTase has been demonstrated to be highly ... -
Ferritin – From iron, through inflammation and autoimmunity, to COVID-19
(Academic Press, 2022)While it took decades to arrive to a conclusion that ferritin is more than an indicator of iron storage level, it took a short period of time through the COVID-19 pandemic to wonder what the reason behind high levels of ... -
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels
(Elsevier B.V., 2022)Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation ... -
Autoimmune post-COVID vaccine syndromes: Does the spectrum of autoimmune/inflammatory syndrome expand
(Springer London Ltd, 2022)To date, around 60% of the world population has been protected by vaccines against SARS-CoV-2, significantly reducing the devastating effect of the pandemic and restoring social economic activity through mass vaccination. ... -
Detection of bladder cancer with feature fusion, transfer learning and CapsNets
(Elsevier B.V., 2022)This paper confronts two approaches to classify bladder lesions shown in white light cystoscopy images when using small datasets: the classical one, where handcrafted-based features feed pattern recognition systems and the ... -
Tumour microenvironment and focal therapy for prostate cancer
(Lippincott Williams & Wilkins, 2022)Purpose of review Although most studies focus on the tumour component of prostate cancer (PCa), increasing attention is being paid to the prostatic tumour microenvironment (TME) and its role in diagnosis, prognosis, and ... -
The mosaic of autoimmunity – Finally discussing in person. The 13th international congress on autoimmunity 2022 (AUTO13) Athens
(Elsevier B.V., 2022)While autoimmunity is a branch of medicine linked to every single organ system via direct and indirect pathways, meeting in person to discuss autoimmunity during the 13th international congress on autoimmunity (AUTO13) ... -
Bradycardia in a patient with severe COVID-19
(NLM (Medline), 2022)BACKGROUND: Heart rate disorders and in particular sinus arrhythmias are known to accompany viral infections. Sinus tachycardia is prevalent in the presence of increased body temperature and respiratory rate. However, ... -
Spatial association of environmental and dietary factors with copd deaths
(Dove Medical Press Ltd, 2022)Introduction: Chronic obstructive pulmonary disease (COPD) remains a significant health concern globally and spatiotemporal investigations on the etiology and progression of COPD are needed to develop more effective and ... -
Is there an association between vitamin B12 level and vitamin D status in children?
(Lippincott Williams and Wilkins, 2022)Vitamin B12 (vit B12) or cobalamin is a water-soluble vitamin that acts as a coenzyme and is effective in the formation of a healthy nervous system and erythrocytes. In its deficiency, except fatigue and weakness, may cause ... -
The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies
(Cell Press, 2022)Small molecule inhibitors have previously been investigated in different studies as possible therapeutics in the treatment of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In the current drug repurposing ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)
(BMC, 2022)Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients ... -
Evaluation of early scoring predictors for expedited care in patients with emphysematous pyelonephritis
(SAGE Publications Inc., 2022)Introduction: Emphysematous pyelonephritis (EPN), an acute necrotizing infection of the kidney and surrounding tissues, is associated with considerable mortality. We evaluated how existing critical care scoring systems ... -
An examination of health care utilization during the COVID-19 pandemic among women with early-stage hormone receptor-positive breast cancer
(BioMed Central Ltd, 2022)Background: Women undergoing treatment for breast cancer require frequent clinic visits for maintenance of therapy. With COVID-19 causing health care disruptions, it is important to learn about how this population’s access ... -
New-onset atrial fibrillation as poor outcome predictor in patients with severe COVID-19
(NLM (Medline), 2022)Tachyarrhythmias are common in patients with coronavirus disease 2019 (COVID-19), in particular those with severe disease. However, newly diagnosed atrial fibrillation (AF) during the course of severe COVID-19 seems to ... -
Good versus poor prescribers: The comparison of prescribing competencies in primary care
(Cambridge University Press, 2022)Aim: To compare the competencies of primary care physicians (PCPs) with poor and good prescribing performance in frequently encountered indications. Background: Primary care centers are one of the mostly visited health ... -
A randomized trial investigating clinical outcomes and stent-related symptoms after placement of a complete intra-ureteric stent on a string versus conventional stent placement
(Wiley, 2022)Objective: To compare stent-related symptoms (SRS) associated with conventional ureteric JJ stent (CUS) placement and SRS associated with placement of a modified complete intra-ureteric stent (CIUS) with extraction suture, ... -
Worldwide distribution, risk factors, and temporal trends of testicular cancer incidence and mortality: A global analysis
(NLM (Medline), 2022)BACKGROUND: Testicular cancer is a common malignancy among young males in western countries. OBJECTIVE: To examine the global disease burden and trends of testicular cancer incidence and mortality by age and country, and ... -
Radical nephroureterectomy for UTUC conferred survival benefits irrespective of age and comorbidities
(Springer, 2022)Purpose We investigated the effects of age, American Society of Anesthesiologists Physical Status Classification (ASA) grading and Charlson Comorbidity Index (CCI) on the survival outcomes of upper tract urothelial carcinoma ...